Detailed information of TA system TA027902

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-RHH
• Location: 845075..845618
• Replicon: chromosome
• Accession: NC_018010
• Organism: Belliella baltica DSM 15883

Toxin (Protein)

• Gene name: parE
• Uniprot ID: I3Z2I1
• Locus tag: BELBA_RS03945
• Protein ID: WP_014771457.1
• Coordinates: 845075..845374 (-)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: I3Z2I2
• Locus tag: BELBA_RS03950
• Protein ID: WP_014771458.1
• Coordinates: 845367..845618 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BELBA_RS03930	841533..843038	-	1506	WP_014771453.1	hypothetical protein	-
BELBA_RS03935	843226..844197	-	972	WP_014771455.1	MoxR family ATPase	-
BELBA_RS03940	844482..845069	-	588	WP_014771456.1	pseudouridine synthase	-
BELBA_RS03945	845075..845374	-	300	WP_014771457.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BELBA_RS03950	845367..845618	-	252	WP_014771458.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
BELBA_RS03955	846005..846229	+	225	WP_157466053.1	hypothetical protein	-
BELBA_RS03960	846277..847254	+	978	WP_014771461.1	hypothetical protein	-
BELBA_RS03965	847427..847825	-	399	WP_014771462.1	type II toxin-antitoxin system VapC family toxin	-
BELBA_RS03970	847822..848061	-	240	WP_014771463.1	hypothetical protein	-
BELBA_RS03975	848289..850382	-	2094	WP_014771464.1	ATP-dependent DNA helicase RecG	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-92)

Antitoxin

• Antitoxin ParD (1-75)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11807.61 Da
• Isoelectric Point: 5.7169

>T27902 WP_014771457.1 NC_018010:c845374-845075 [Belliella baltica DSM 15883]
MGKYFLTAKALSDLSDIYEYTYYFWSENHADKYYQNLIDCFQSLAKSPRIGRAYDEIDLGLLGFPMRKHVIFYKLYAEEE
IEIIRILSSNMDLKKLIKE

Nucleotide

• Length: 300 bp

>T27902 NC_018010:c845374-845075 [Belliella baltica DSM 15883]
ATGGGTAAATATTTTTTAACTGCTAAAGCGCTGAGTGATTTATCGGATATTTATGAATACACCTACTATTTTTGGTCAGA
AAATCATGCAGATAAATACTATCAAAATTTGATCGATTGTTTTCAAAGCTTAGCAAAAAGCCCAAGAATTGGAAGAGCGT
ATGACGAAATAGATCTTGGCTTGCTTGGATTTCCAATGAGGAAACATGTGATTTTTTACAAACTTTATGCTGAAGAAGAA
ATTGAAATAATAAGAATTCTAAGTTCAAATATGGATTTGAAAAAGCTTATCAAAGAATAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9297.56 Da
• Isoelectric Point: 8.5687

>AT27902 WP_014771458.1 NC_018010:c845618-845367 [Belliella baltica DSM 15883]
MGRNTSVSLGSYFEDFVDSKISEGRFKNASEVIRAGLRLLEEEEGKIKLLKNAIQEGIESGRVKDFDSDNHLKLLKAKLQ
KNG

Nucleotide

• Length: 252 bp

>AT27902 NC_018010:c845618-845367 [Belliella baltica DSM 15883]
ATGGGGCGTAATACATCAGTTTCTTTAGGGAGCTATTTCGAAGATTTCGTTGATAGTAAAATATCAGAAGGACGGTTTAA
AAATGCAAGCGAGGTAATTAGAGCTGGTCTGCGACTTTTGGAAGAAGAAGAAGGTAAGATTAAGTTACTAAAAAATGCAA
TTCAAGAAGGAATAGAAAGTGGAAGAGTAAAAGATTTTGATTCTGATAATCATTTAAAACTTTTAAAGGCAAAGCTCCAA
AAGAATGGGTAA

Structures

Toxin

• AlphaFold DB: I3Z2I1

Antitoxin

• AlphaFold DB: I3Z2I2