Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 89017..89552 Replicon plasmid paPv3
Accession NZ_CP123507
Organism Arsenophonus nasoniae strain aPv

Toxin (Protein)


Gene name relE Uniprot ID A0A4P7L9F7
Locus tag QE210_RS19460 Protein ID WP_026824095.1
Coordinates 89017..89304 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A4V1BXI0
Locus tag QE210_RS19465 Protein ID WP_026824096.1
Coordinates 89301..89552 (-) Length 84 a.a.

Genomic Context

QE210_RS19445QE210_RS19450QE210_RS19455QE210_RS19470QE210_RS19475QE210_RS19480QE210_RS19485QE210_RS19495QE210_RS19440QE210_RS19460QE210_RS19465QE210_RS19490
Location: 85754..86656 (903 bp)
Type: Others
Protein ID: Protein_104
Location: 86805..88469 (1665 bp)
Type: Others
Protein ID: WP_280626390.1
Location: 88477..88884 (408 bp)
Type: Others
Protein ID: WP_280626391.1
Location: 89634..90713 (1080 bp)
Type: Others
Protein ID: WP_280626792.1
Location: 90717..91343 (627 bp)
Type: Others
Protein ID: WP_280626793.1
Location: 91437..91901 (465 bp)
Type: Others
Protein ID: WP_280626855.1
Location: 92060..92644 (585 bp)
Type: Others
Protein ID: Protein_112
Location: 94090..94248 (159 bp)
Type: Others
Protein ID: Protein_114
Location: 84086..85126 (1041 bp)
Type: Others
Protein ID: WP_280626854.1
Location: 89017..89304 (288 bp)
Type: Toxin
Protein ID: WP_026824095.1
Location: 89301..89552 (252 bp)
Type: Antitoxin
Protein ID: WP_026824096.1
Location: 92805..94004 (1200 bp)
Type: Others
Protein ID: WP_280624651.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QE210_RS19440 (QE210_19350)84086..85126-1041WP_280626854.1IS481 family transposase-
QE210_RS19445 (QE210_19355)85754..86656+903Protein_104conjugative transfer relaxase/helicase TraI-
QE210_RS19450 (QE210_19360)86805..88469+1665WP_280626390.1type III secretion system effector inositol phosphate phosphatase-
QE210_RS19455 (QE210_19365)88477..88884+408WP_280626391.1hypothetical protein-
QE210_RS19460 (QE210_19370)89017..89304-288WP_026824095.1type II toxin-antitoxin system RelE/ParE family toxinToxin
QE210_RS19465 (QE210_19375)89301..89552-252WP_026824096.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
QE210_RS19470 (QE210_19380)89634..90713+1080WP_280626792.1type II secretion system F family protein-
QE210_RS19475 (QE210_19385)90717..91343+627WP_280626793.1type 4 pilus major pilin-
QE210_RS19480 (QE210_19390)91437..91901+465WP_280626855.1lytic transglycosylase domain-containing protein-
QE210_RS19485 (QE210_19395)92060..92644+585Protein_112helix-turn-helix domain-containing protein-
QE210_RS19490 (QE210_19400)92805..94004-1200WP_280624651.1IS91 family transposase-
QE210_RS19495 (QE210_19405)94090..94248+159Protein_114phospholipase D-like domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..9425094250
-flankIS/Tn--84086..85033947
-flankIS/Tn--92060..92656596


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11252.32 Da        Isoelectric Point: 10.9743

>T279018 WP_026824095.1 NZ_CP123507:c89304-89017 [Arsenophonus nasoniae]
MIYKVKFRTDALKEWNNLDRSIQQQFARKLKKCAENPHIPAARLRGMQNCYKIKLRSSGFRLVYQIFKDELIIAVVAVGK
REHSEVYKLASKRLR

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9362.58 Da        Isoelectric Point: 4.0543

>AT279018 WP_026824096.1 NZ_CP123507:c89552-89301 [Arsenophonus nasoniae]
MPTTILSTTTASITELKTNPMATVNSGDGYPVAILNRNQPAFYCIPAELYEQMLEFIDDQELANLVKERAEQTLHDVNLD
RYL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A4P7L9F7

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A4V1BXI0

References