Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 2891773..2892401 Replicon chromosome
Accession NZ_CP123504
Organism Arsenophonus nasoniae strain aPv

Toxin (Protein)


Gene name Hha Uniprot ID D2TWD5
Locus tag QE210_RS14550 Protein ID WP_026821483.1
Coordinates 2892198..2892401 (+) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag QE210_RS14545 Protein ID WP_280624621.1
Coordinates 2891773..2892141 (+) Length 123 a.a.

Genomic Context

QE210_RS14535QE210_RS14540QE210_RS14545QE210_RS14550QE210_RS14560QE210_RS14565
Location: 2886927..2888090 (1164 bp)
Type: Others
Protein ID: WP_026821486.1
Location: 2888133..2891252 (3120 bp)
Type: Others
Protein ID: WP_280624620.1
Location: 2891773..2892141 (369 bp)
Type: Antitoxin
Protein ID: WP_280624621.1
Location: 2892198..2892401 (204 bp)
Type: Toxin
Protein ID: WP_026821483.1
Location: 2893199..2894986 (1788 bp)
Type: Others
Protein ID: WP_280624623.1
Location: 2894973..2896721 (1749 bp)
Type: Others
Protein ID: WP_280624625.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QE210_RS14535 (QE210_14465)2886927..2888090+1164WP_026821486.1efflux RND transporter periplasmic adaptor subunit-
QE210_RS14540 (QE210_14470)2888133..2891252+3120WP_280624620.1efflux RND transporter permease subunit-
QE210_RS14545 (QE210_14475)2891773..2892141+369WP_280624621.1Hha toxicity modulator TomBAntitoxin
QE210_RS14550 (QE210_14480)2892198..2892401+204WP_026821483.1HHA domain-containing proteinToxin
QE210_RS14560 (QE210_14490)2893199..2894986-1788WP_280624623.1SmdB family multidrug efflux ABC transporter permease/ATP-binding protein-
QE210_RS14565 (QE210_14495)2894973..2896721-1749WP_280624625.1SmdA family multidrug ABC transporter permease/ATP-binding protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-114)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8133.45 Da        Isoelectric Point: 6.9767

>T279015 WP_026821483.1 NZ_CP123504:2892198-2892401 [Arsenophonus nasoniae]
MTKIDYLMRLRKCTTIETLERVIEKNKYELSEDELELFYSAADHRLAELTMNKLYDKIPSSVWKYVR

Download         Length: 204 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14426.39 Da        Isoelectric Point: 5.1197

>AT279015 WP_280624621.1 NZ_CP123504:2891773-2892141 [Arsenophonus nasoniae]
MDEYSPRSYDILVLKYLCDALHRDAMLTLHRTKTHWKNDLGSDQNVKFNVLIDHITDFIGQFKLKYPNNVNLFIFIDEYL
DETYSLFGKPVMSLTDISDWQKMNEHLSEILTNDIKYSLSNT

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBD2TWD5

Antitoxin

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Source
ID
Structure
No matching records found

References