Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 2891773..2892401 Replicon chromosome
Accession NZ_CP123504
Organism Arsenophonus nasoniae strain aPv

Toxin (Protein)


Gene name Hha Uniprot ID D2TWD5
Locus tag QE210_RS14550 Protein ID WP_026821483.1
Coordinates 2892198..2892401 (+) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag QE210_RS14545 Protein ID WP_280624621.1
Coordinates 2891773..2892141 (+) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QE210_RS14535 (QE210_14465) 2886927..2888090 + 1164 WP_026821486.1 efflux RND transporter periplasmic adaptor subunit -
QE210_RS14540 (QE210_14470) 2888133..2891252 + 3120 WP_280624620.1 efflux RND transporter permease subunit -
QE210_RS14545 (QE210_14475) 2891773..2892141 + 369 WP_280624621.1 Hha toxicity modulator TomB Antitoxin
QE210_RS14550 (QE210_14480) 2892198..2892401 + 204 WP_026821483.1 HHA domain-containing protein Toxin
QE210_RS14560 (QE210_14490) 2893199..2894986 - 1788 WP_280624623.1 SmdB family multidrug efflux ABC transporter permease/ATP-binding protein -
QE210_RS14565 (QE210_14495) 2894973..2896721 - 1749 WP_280624625.1 SmdA family multidrug ABC transporter permease/ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-114)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8133.45 Da        Isoelectric Point: 6.9767

>T279015 WP_026821483.1 NZ_CP123504:2892198-2892401 [Arsenophonus nasoniae]
MTKIDYLMRLRKCTTIETLERVIEKNKYELSEDELELFYSAADHRLAELTMNKLYDKIPSSVWKYVR

Download         Length: 204 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14426.39 Da        Isoelectric Point: 5.1197

>AT279015 WP_280624621.1 NZ_CP123504:2891773-2892141 [Arsenophonus nasoniae]
MDEYSPRSYDILVLKYLCDALHRDAMLTLHRTKTHWKNDLGSDQNVKFNVLIDHITDFIGQFKLKYPNNVNLFIFIDEYL
DETYSLFGKPVMSLTDISDWQKMNEHLSEILTNDIKYSLSNT

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB D2TWD5

Antitoxin

Source ID Structure

References