Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2639046..2639700 Replicon chromosome
Accession NZ_CP123504
Organism Arsenophonus nasoniae strain aPv

Toxin (Protein)


Gene name cptA Uniprot ID A0A4P7L3M1
Locus tag QE210_RS13195 Protein ID WP_026821813.1
Coordinates 2639046..2639453 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A4P7KWA0
Locus tag QE210_RS13200 Protein ID WP_026821812.1
Coordinates 2639434..2639700 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QE210_RS13175 (QE210_13110) 2634430..2634621 + 192 WP_280624333.1 hypothetical protein -
QE210_RS13180 (QE210_13115) 2634904..2636193 + 1290 WP_280624334.1 hypothetical protein -
QE210_RS13185 (QE210_13120) 2636714..2638027 + 1314 WP_280624335.1 S8 family serine peptidase -
QE210_RS13190 (QE210_13125) 2638512..2639030 + 519 WP_026821814.1 flavodoxin FldB -
QE210_RS13195 (QE210_13130) 2639046..2639453 - 408 WP_026821813.1 protein YgfX Toxin
QE210_RS13200 (QE210_13135) 2639434..2639700 - 267 WP_026821812.1 FAD assembly factor SdhE Antitoxin
QE210_RS13205 (QE210_13140) 2639960..2640946 + 987 WP_280624336.1 tRNA-modifying protein YgfZ -
QE210_RS13210 (QE210_13145) 2641801..2642139 - 339 WP_280624338.1 hypothetical protein -
QE210_RS13215 (QE210_13150) 2642384..2643220 - 837 WP_280624340.1 hypothetical protein -
QE210_RS13220 (QE210_13155) 2643312..2644169 - 858 WP_280624342.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15888.82 Da        Isoelectric Point: 10.8101

>T279014 WP_026821813.1 NZ_CP123504:c2639453-2639046 [Arsenophonus nasoniae]
VVLWKFNINVSWLTQLFSTGVHVGIGLLVFFSSWPPNNLVTWLIATLLIVASWVRSQKNISRCKGSIVLLNGNKIQWKKS
EWLIVKKPWFCFFGVKLTLRSWQCNKRIRLWIASDSMPEEEWRNLNQLLLQYPDI

Download         Length: 408 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10612.15 Da        Isoelectric Point: 5.1149

>AT279014 WP_026821812.1 NZ_CP123504:c2639700-2639434 [Arsenophonus nasoniae]
MDINHKPRIHWACRRGMRELDIAIMPFFEYEYDSLTEDEKCLFVRLLECADPDLFNWLMNHGRPDDDGLYHMIQLIQSRN
KQRGSLEI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7L3M1

Antitoxin

Source ID Structure
AlphaFold DB A0A4P7KWA0

References