Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 44474..45008 Replicon plasmid paPb1
Accession NZ_CP123500
Organism Arsenophonus sp. aPb

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QE177_RS14640 Protein ID WP_280552407.1
Coordinates 44474..44767 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QE177_RS14645 Protein ID WP_280552409.1
Coordinates 44757..45008 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QE177_RS14610 (QE177_14610) 40380..41093 + 714 WP_280552395.1 VUT family protein -
QE177_RS14615 (QE177_14615) 41071..41799 + 729 WP_280552397.1 metallophosphoesterase -
QE177_RS14620 (QE177_14620) 41796..42317 - 522 WP_280552398.1 hypothetical protein -
QE177_RS14625 (QE177_14625) 42320..42958 - 639 WP_280552400.1 helix-turn-helix domain-containing protein -
QE177_RS14630 (QE177_14630) 43170..43508 + 339 WP_280552403.1 type IV conjugative transfer system pilin TraA -
QE177_RS14635 (QE177_14635) 43778..44326 + 549 WP_280552405.1 hypothetical protein -
QE177_RS14640 (QE177_14640) 44474..44767 - 294 WP_280552407.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QE177_RS14645 (QE177_14645) 44757..45008 - 252 WP_280552409.1 plasmid stabilization protein Antitoxin
QE177_RS14650 (QE177_14650) 45090..47132 + 2043 WP_280552305.1 type IV conjugative transfer system coupling protein TraD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..89842 89842


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11643.60 Da        Isoelectric Point: 10.4957

>T279011 WP_280552407.1 NZ_CP123500:c44767-44474 [Arsenophonus sp. aPb]
MNYELQFEKRALKEWKKLPQPIKEQFKKKLNERLQNPHIISAKLSGSINRYKIKLRSSGYRLVYEVDDEKITVYVIAVGK
RERSEVYILAKDRNIFN

Download         Length: 294 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9410.80 Da        Isoelectric Point: 4.5799

>AT279011 WP_280552409.1 NZ_CP123500:c45008-44757 [Arsenophonus sp. aPb]
MVYRILTNTVASITELKKNPMGTMANAEGEAVAILNHNEPAFYCVPPELFAYFQELLEDAELNDIVDKRKHNAKFVKVDI
NEL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References