Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2336712..2337366 Replicon chromosome
Accession NZ_CP123499
Organism Arsenophonus sp. aPb

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag QE177_RS10460 Protein ID WP_180558768.1
Coordinates 2336712..2337119 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A4P7KWA0
Locus tag QE177_RS10465 Protein ID WP_026821812.1
Coordinates 2337100..2337366 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QE177_RS10445 (QE177_10445) 2332102..2333889 + 1788 WP_280549402.1 hypothetical protein -
QE177_RS10450 (QE177_10450) 2334382..2335695 + 1314 WP_280549404.1 S8 family serine peptidase -
QE177_RS10455 (QE177_10455) 2336178..2336696 + 519 WP_280549407.1 flavodoxin FldB -
QE177_RS10460 (QE177_10460) 2336712..2337119 - 408 WP_180558768.1 protein YgfX Toxin
QE177_RS10465 (QE177_10465) 2337100..2337366 - 267 WP_026821812.1 FAD assembly factor SdhE Antitoxin
QE177_RS10470 (QE177_10470) 2337626..2338612 + 987 WP_280549415.1 tRNA-modifying protein YgfZ -
QE177_RS10475 (QE177_10475) 2339483..2339815 - 333 WP_280549418.1 hypothetical protein -
QE177_RS10480 (QE177_10480) 2340066..2340902 - 837 WP_280549420.1 hypothetical protein -
QE177_RS10485 (QE177_10485) 2340995..2341852 - 858 WP_280549422.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15888.82 Da        Isoelectric Point: 10.8101

>T279010 WP_180558768.1 NZ_CP123499:c2337119-2336712 [Arsenophonus sp. aPb]
VVLWKFNINVSWLTQLFSTGVHVGIGLLVFFSSWPPNNLVTWLIATLLIVASWVRSQKNISRCKGSLVLLNGNKIQWKKS
EWLIVKKPWFCFFGVKLTLRSWQCNKRIRLWIASDSMPEEEWRNLNQLLLQYPDI

Download         Length: 408 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10612.15 Da        Isoelectric Point: 5.1149

>AT279010 WP_026821812.1 NZ_CP123499:c2337366-2337100 [Arsenophonus sp. aPb]
MDINHKPRIHWACRRGMRELDIAIMPFFEYEYDSLTEDEKCLFVRLLECADPDLFNWLMNHGRPDDDGLYHMIQLIQSRN
KQRGSLEI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A4P7KWA0

References