Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 2250792..2251420 Replicon chromosome
Accession NZ_CP123498
Organism Arsenophonus nasoniae strain aIh

Toxin (Protein)


Gene name Hha Uniprot ID -
Locus tag QE207_RS12780 Protein ID WP_280628822.1
Coordinates 2251217..2251420 (+) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag QE207_RS12775 Protein ID WP_280628821.1
Coordinates 2250792..2251160 (+) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QE207_RS12765 (QE207_12755) 2245945..2247108 + 1164 WP_280628819.1 efflux RND transporter periplasmic adaptor subunit -
QE207_RS12770 (QE207_12760) 2247151..2250270 + 3120 WP_280628820.1 efflux RND transporter permease subunit -
QE207_RS12775 (QE207_12765) 2250792..2251160 + 369 WP_280628821.1 Hha toxicity modulator TomB Antitoxin
QE207_RS12780 (QE207_12770) 2251217..2251420 + 204 WP_280628822.1 HHA domain-containing protein Toxin
QE207_RS12790 (QE207_12780) 2252217..2254004 - 1788 WP_280628823.1 SmdB family multidrug efflux ABC transporter permease/ATP-binding protein -
QE207_RS12795 (QE207_12785) 2253991..2255739 - 1749 WP_280628824.1 SmdA family multidrug ABC transporter permease/ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-114)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8193.54 Da        Isoelectric Point: 6.9767

>T279006 WP_280628822.1 NZ_CP123498:2251217-2251420 [Arsenophonus nasoniae]
MTKIDYLMRLRKCTTIETLERVIEKNKYELFEDELELFYSAADHRLAELTMNKLYDKIPSSVWKYVR

Download         Length: 204 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14437.42 Da        Isoelectric Point: 5.1197

>AT279006 WP_280628821.1 NZ_CP123498:2250792-2251160 [Arsenophonus nasoniae]
MDEYSPRSYDILVLKYLCDALHRDAMLTLHRTKTHWKNDLGSDQNVKFNVLIDHITDFIGQFKLKYPNNVNLFIFIDEYL
DETYNLFGKPVMSLTDISDWQKMNEHLAEILTNDIKYSLSNT

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References