Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 2250792..2251420 Replicon chromosome
Accession NZ_CP123498
Organism Arsenophonus nasoniae strain aIh

Toxin (Protein)


Gene name Hha Uniprot ID -
Locus tag QE207_RS12780 Protein ID WP_280628822.1
Coordinates 2251217..2251420 (+) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag QE207_RS12775 Protein ID WP_280628821.1
Coordinates 2250792..2251160 (+) Length 123 a.a.

Genomic Context

QE207_RS12765QE207_RS12770QE207_RS12775QE207_RS12780QE207_RS12790QE207_RS12795
Location: 2245945..2247108 (1164 bp)
Type: Others
Protein ID: WP_280628819.1
Location: 2247151..2250270 (3120 bp)
Type: Others
Protein ID: WP_280628820.1
Location: 2250792..2251160 (369 bp)
Type: Antitoxin
Protein ID: WP_280628821.1
Location: 2251217..2251420 (204 bp)
Type: Toxin
Protein ID: WP_280628822.1
Location: 2252217..2254004 (1788 bp)
Type: Others
Protein ID: WP_280628823.1
Location: 2253991..2255739 (1749 bp)
Type: Others
Protein ID: WP_280628824.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QE207_RS12765 (QE207_12755)2245945..2247108+1164WP_280628819.1efflux RND transporter periplasmic adaptor subunit-
QE207_RS12770 (QE207_12760)2247151..2250270+3120WP_280628820.1efflux RND transporter permease subunit-
QE207_RS12775 (QE207_12765)2250792..2251160+369WP_280628821.1Hha toxicity modulator TomBAntitoxin
QE207_RS12780 (QE207_12770)2251217..2251420+204WP_280628822.1HHA domain-containing proteinToxin
QE207_RS12790 (QE207_12780)2252217..2254004-1788WP_280628823.1SmdB family multidrug efflux ABC transporter permease/ATP-binding protein-
QE207_RS12795 (QE207_12785)2253991..2255739-1749WP_280628824.1SmdA family multidrug ABC transporter permease/ATP-binding protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-114)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8193.54 Da        Isoelectric Point: 6.9767

>T279006 WP_280628822.1 NZ_CP123498:2251217-2251420 [Arsenophonus nasoniae]
MTKIDYLMRLRKCTTIETLERVIEKNKYELFEDELELFYSAADHRLAELTMNKLYDKIPSSVWKYVR

Download         Length: 204 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14437.42 Da        Isoelectric Point: 5.1197

>AT279006 WP_280628821.1 NZ_CP123498:2250792-2251160 [Arsenophonus nasoniae]
MDEYSPRSYDILVLKYLCDALHRDAMLTLHRTKTHWKNDLGSDQNVKFNVLIDHITDFIGQFKLKYPNNVNLFIFIDEYL
DETYNLFGKPVMSLTDISDWQKMNEHLAEILTNDIKYSLSNT

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References