Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-couple_hipB
Location 1800986..1802625 Replicon chromosome
Accession NZ_CP123498
Organism Arsenophonus nasoniae strain aIh

Toxin (Protein)


Gene name HipA3 Uniprot ID -
Locus tag QE207_RS10855 Protein ID WP_280628594.1
Coordinates 1800986..1802302 (-) Length 439 a.a.

Antitoxin (Protein)


Gene name HipB3 Uniprot ID -
Locus tag QE207_RS10860 Protein ID WP_026823614.1
Coordinates 1802296..1802625 (-) Length 110 a.a.

Genomic Context

QE207_RS10840QE207_RS10845QE207_RS10850QE207_RS10865QE207_RS10875QE207_RS10835QE207_RS10855QE207_RS10860QE207_RS10870
Location: 1799774..1800451 (678 bp)
Type: Others
Protein ID: WP_280628592.1
Location: 1800448..1800585 (138 bp)
Type: Others
Protein ID: WP_280628593.1
Location: 1800696..1800794 (99 bp)
Type: Others
Protein ID: WP_280626126.1
Location: 1802912..1803718 (807 bp)
Type: Others
Protein ID: WP_280628595.1
Location: 1804870..1805460 (591 bp)
Type: Others
Protein ID: WP_026823615.1
Location: 1797983..1798780 (798 bp)
Type: Others
Protein ID: WP_280628591.1
Location: 1800986..1802302 (1317 bp)
Type: Toxin
Protein ID: WP_280628594.1
Location: 1802296..1802625 (330 bp)
Type: Antitoxin
Protein ID: WP_026823614.1
Location: 1803731..1804642 (912 bp)
Type: Others
Protein ID: WP_280628596.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QE207_RS10835 (QE207_10825)1797983..1798780-798WP_280628591.1hypothetical protein-
QE207_RS10840 (QE207_10830)1799774..1800451+678WP_280628592.1ankyrin repeat domain-containing protein-
QE207_RS10845 (QE207_10835)1800448..1800585+138WP_280628593.1hypothetical protein-
QE207_RS10850 (QE207_10840)1800696..1800794+99WP_280626126.1hypothetical protein-
QE207_RS10855 (QE207_10845)1800986..1802302-1317WP_280628594.1type II toxin-antitoxin system HipA family toxinToxin
QE207_RS10860 (QE207_10850)1802296..1802625-330WP_026823614.1helix-turn-helix transcriptional regulatorAntitoxin
QE207_RS10865 (QE207_10855)1802912..1803718+807WP_280628595.12,5-didehydrogluconate reductase DkgB-
QE207_RS10870 (QE207_10860)1803731..1804642-912WP_280628596.1DNA-binding transcriptional regulator YafC-
QE207_RS10875 (QE207_10865)1804870..1805460+591WP_026823615.1NAD(P)H-dependent oxidoreductase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(174-411)

Antitoxin

Cro/C1-type helix-turn-helix domain

(19-65)


Sequences

Toxin        


Download         Length: 439 a.a.        Molecular weight: 49537.74 Da        Isoelectric Point: 9.0448

>T279004 WP_280628594.1 NZ_CP123498:c1802302-1800986 [Arsenophonus nasoniae]
MVMEVINVNYKQHEVGAVSFDTSKGLGFFEYNSRFIKQGIELSPLKMPLATRIYSFPELDFNTFKGLPGLIADSLPDDFG
NAVLNAWVATMGKSPDTITPLQRLQYTGKRGMGALEYVPATRIKSLNASQQVEISSLVAITQEILDSRQKFTVELHKNGQ
EDREAMMALLSVGMSAGGARPKAVLAFNQDFTQVRSGQTNVPDGFTHYLIKFDGVSEHNKNQQTFGDPVGFGAMEYVYYL
LATRCGIEMMPCRLLAEGNRRHFITQRFDRFGNKKRHVQTLNGLAHVDYKKPGSFSYAELFGVARQLKLSAKEAEQLLKR
MTFNIVARNHDDHAKNFSFMLKGDKWMLAPAYDLAYSYKPGSKWVNSHWMSLNGKRDNFSRQDFYSLEKLSPLFTREMIN
GIIDETIEKVSEWQKLAVEFAVPNLLAQEINANLCLNI

Download         Length: 1317 bp

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12102.85 Da        Isoelectric Point: 6.4752

>AT279004 WP_026823614.1 NZ_CP123498:c1802625-1802296 [Arsenophonus nasoniae]
MSIFEESASAIAAELGERLKQARLNHDLTQAEVAELSGISRKTVLNAEKGNVQLENLIAIMAALNLLEQLDLFLPKQDIS
PIQLAKLQGKKRQRASGHRKNNTEDLAEW

Download         Length: 330 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References