Detailed information of TA system TA027900

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-pasA/RelE-HTH
• Location: 2086996..2087329
• Replicon: chromosome
• Accession: NC_018002
• Organism: Sulfurospirillum barnesii SES-3

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: SULBA_RS12885
• Protein ID: WP_156790578.1
• Coordinates: 2086996..2087178 (-)
• Length: 61 a.a.

Antitoxin (Protein)

• Gene name: pasA
• Uniprot ID: -
• Locus tag: SULBA_RS12975
• Protein ID: WP_156790539.1
• Coordinates: 2087162..2087329 (-)
• Length: 56 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SULBA_RS10460	2082536..2083546	+	1011	WP_014770259.1	hypothetical protein	-
SULBA_RS10465	2083687..2084889	-	1203	WP_014768976.1	IS256 family transposase	-
SULBA_RS12810	2085434..2086258	+	825	WP_083834418.1	signal peptidase I	-
SULBA_RS10475	2086452..2086826	+	375	WP_014770261.1	hypothetical protein	-
SULBA_RS12885	2086996..2087178	-	183	WP_156790578.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
SULBA_RS12975	2087162..2087329	-	168	WP_156790539.1	hypothetical protein	Antitoxin
SULBA_RS10480	2087510..2087986	+	477	WP_014770262.1	glutathione peroxidase	-
SULBA_RS10485	2088124..2088942	+	819	WP_014770263.1	sirohydrochlorin cobaltochelatase	-
SULBA_RS10490	2088950..2089615	+	666	WP_156790579.1	cobalt-precorrin-2 C(20)-methyltransferase	-
SULBA_RS10495	2089612..2090322	+	711	WP_014770265.1	precorrin-8X methylmutase	-
SULBA_RS10500	2090312..2090761	+	450	WP_041671850.1	(2Fe-2S) ferredoxin domain-containing protein	-
SULBA_RS10505	2090754..2091773	+	1020	WP_014770266.1	cobalt-precorrin-5B (C(1))-methyltransferase CbiD	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-57)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 61 a.a.
• Molecular weight: 7245.42 Da
• Isoelectric Point: 10.2553

>T27900 WP_156790578.1 NC_018002:c2087178-2086996 [Sulfurospirillum barnesii SES-3]
IKHLSDCTDPRDKGKKRKGKLKEFWRYRVGDYRIITKITDQEITILVLKVAHRKDVYEDQ

Nucleotide

• Length: 183 bp

>T27900 NC_018002:c2087178-2086996 [Sulfurospirillum barnesii SES-3]
ATCAAACACCTGAGTGACTGTACTGACCCAAGAGACAAAGGCAAGAAACGCAAAGGCAAACTCAAAGAATTTTGGCGATA
TAGAGTAGGCGATTATCGCATCATTACCAAAATCACCGATCAAGAAATCACGATTTTAGTTTTGAAGGTGGCGCATCGAA
AAGATGTGTATGAGGATCAGTAA

Antitoxin

Protein

• Length: 56 a.a.
• Molecular weight: 6598.36 Da
• Isoelectric Point: 4.3308

>AT27900 WP_156790539.1 NC_018002:c2087329-2087162 [Sulfurospirillum barnesii SES-3]
MATSIRLDDSFEARLTRLATLTDRPKSFYIRKLFEDYFENLEDYYLAEKADQTPE

Nucleotide

• Length: 168 bp

>AT27900 NC_018002:c2087329-2087162 [Sulfurospirillum barnesii SES-3]
ATGGCTACTTCTATTAGACTCGATGATAGTTTTGAAGCACGATTGACTCGGTTAGCAACCTTAACAGATCGTCCAAAATC
TTTTTATATTAGAAAGTTGTTTGAAGATTATTTTGAGAATTTGGAAGATTATTATTTAGCAGAAAAAGCAGATCAAACAC
CTGAGTGA