Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 544814..545396 Replicon chromosome
Accession NZ_CP123498
Organism Arsenophonus nasoniae strain aIh

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag QE207_RS04460 Protein ID WP_280629590.1
Coordinates 545100..545396 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QE207_RS04455 Protein ID WP_280629589.1
Coordinates 544814..545098 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QE207_RS04430 (QE207_04425) 540184..541224 - 1041 WP_280628258.1 IS21 family transposase -
QE207_RS04435 (QE207_04430) 541314..542264 + 951 Protein_475 helix-turn-helix domain-containing protein -
QE207_RS04440 (QE207_04435) 542273..542413 + 141 WP_280629587.1 hypothetical protein -
QE207_RS04445 (QE207_04440) 542547..543230 + 684 Protein_477 IS6 family transposase -
QE207_RS04450 (QE207_04445) 543253..544530 - 1278 WP_280629588.1 SMEK domain-containing protein -
QE207_RS04455 (QE207_04450) 544814..545098 - 285 WP_280629589.1 putative addiction module antidote protein Antitoxin
QE207_RS04460 (QE207_04455) 545100..545396 - 297 WP_280629590.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QE207_RS04465 (QE207_04460) 546076..546759 + 684 Protein_481 IS6 family transposase -
QE207_RS04470 (QE207_04465) 547293..547562 - 270 WP_280629591.1 hypothetical protein -
QE207_RS04475 (QE207_04470) 547576..550359 + 2784 WP_280629592.1 autotransporter outer membrane beta-barrel domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 520832..595437 74605


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-91)

Antitoxin

Cro/C1-type helix-turn-helix domain

(47-89)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11254.13 Da        Isoelectric Point: 10.1687

>T278998 WP_280629590.1 NZ_CP123498:c545396-545100 [Arsenophonus nasoniae]
MIEIRQTEEVKKWLKGLKDKIAKAKILTRIERMKEGNYGDVEPIGDGYSELKIHQGKGYRVYFATRNNEIILLLCGGDKA
TQQADIKKAKQIAKQWGF

Download         Length: 297 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10323.64 Da        Isoelectric Point: 5.1007

>AT278998 WP_280629589.1 NZ_CP123498:c545098-544814 [Arsenophonus nasoniae]
MKTKPELFDVVDYLDNEEDIQAYLNAALDEDDENYFLVALGNVARARNISHLSKETGMSREGIYKALSGAGNPSFKTISK
ISKALGLKLHFSGA

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References