Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-DinJ
Location 1542238..1542767 Replicon chromosome
Accession NC_018002
Organism Sulfurospirillum barnesii SES-3

Toxin (Protein)


Gene name yoeB Uniprot ID I3XY30
Locus tag SULBA_RS07750 Protein ID WP_014769732.1
Coordinates 1542238..1542507 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID I3XY31
Locus tag SULBA_RS07755 Protein ID WP_014769733.1
Coordinates 1542504..1542767 (-) Length 88 a.a.

Genomic Context

SULBA_RS07745SULBA_RS07765SULBA_RS07770SULBA_RS07775SULBA_RS07720SULBA_RS07725SULBA_RS07730SULBA_RS07735SULBA_RS07740SULBA_RS07750SULBA_RS07755SULBA_RS07760
Location: 1541442..1542200 (759 bp)
Type: Others
Protein ID: WP_014769731.1
Location: 1543746..1544060 (315 bp)
Type: Others
Protein ID: WP_014769735.1
Location: 1544057..1545310 (1254 bp)
Type: Others
Protein ID: WP_014769736.1
Location: 1545429..1547042 (1614 bp)
Type: Others
Protein ID: WP_014769737.1
Location: 1537912..1539039 (1128 bp)
Type: Others
Protein ID: WP_014769726.1
Location: 1539036..1539419 (384 bp)
Type: Others
Protein ID: WP_041671830.1
Location: 1539410..1539658 (249 bp)
Type: Others
Protein ID: WP_014769728.1
Location: 1539655..1540728 (1074 bp)
Type: Others
Protein ID: WP_014769729.1
Location: 1540725..1541213 (489 bp)
Type: Others
Protein ID: WP_014769730.1
Location: 1542238..1542507 (270 bp)
Type: Toxin
Protein ID: WP_014769732.1
Location: 1542504..1542767 (264 bp)
Type: Antitoxin
Protein ID: WP_014769733.1
Location: 1542823..1543620 (798 bp)
Type: Others
Protein ID: WP_014769734.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
SULBA_RS077201537912..1539039-1128WP_014769726.1CCA tRNA nucleotidyltransferase-
SULBA_RS077251539036..1539419-384WP_041671830.1hypothetical protein-
SULBA_RS077301539410..1539658-249WP_014769728.1hypothetical protein-
SULBA_RS077351539655..1540728-1074WP_014769729.13-isopropylmalate dehydrogenase-
SULBA_RS077401540725..1541213-489WP_014769730.13-isopropylmalate dehydratase small subunit-
SULBA_RS077451541442..1542200+759WP_014769731.1hypothetical protein-
SULBA_RS077501542238..1542507-270WP_014769732.1Txe/YoeB family addiction module toxinToxin
SULBA_RS077551542504..1542767-264WP_014769733.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
SULBA_RS077601542823..1543620-798WP_014769734.1ATP-binding cassette domain-containing protein-
SULBA_RS077651543746..1544060+315WP_014769735.1metalloregulator ArsR/SmtB family transcription factor-
SULBA_RS077701544057..1545310+1254WP_014769736.1arsenic transporter-
SULBA_RS077751545429..1547042+1614WP_014769737.1methyl-accepting chemotaxis protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-86)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(6-50)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10629.04 Da        Isoelectric Point: 7.9819

>T27899 WP_014769732.1 NC_018002:c1542507-1542238 [Sulfurospirillum barnesii SES-3]
MSYSIVFTQIAWDEYLSWQSEDKKTLKRINQLLSDIMRNGNSGIGKPERLRGDLSEYWSRRIDEKNRIVYRIVEESIEVV
QCKTHYADK

Download         Length: 270 bp

>T27899 NC_018002:c1542507-1542238 [Sulfurospirillum barnesii SES-3]
ATGAGCTACTCAATCGTTTTTACGCAGATAGCGTGGGACGAATATTTATCGTGGCAGAGTGAGGATAAAAAGACGCTAAA
ACGCATCAATCAACTCTTATCAGACATCATGCGAAATGGTAACTCAGGCATCGGTAAACCTGAACGGCTAAGAGGCGATT
TGTCGGAGTATTGGAGTCGTAGGATTGATGAGAAAAACCGCATCGTTTACCGCATTGTAGAAGAGTCCATCGAAGTGGTA
CAATGCAAAACGCATTATGCGGATAAGTAG

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9956.40 Da        Isoelectric Point: 6.3285

>AT27899 WP_014769733.1 NC_018002:c1542767-1542504 [Sulfurospirillum barnesii SES-3]
MAQVNINIRMDETVKKQAEELFNELGLNMTTAFNMFVRQALNRGGIPFEVVRKDAFYSPYNQEKLRESIASTDKTVKSLD
ALEKLAQ

Download         Length: 264 bp

>AT27899 NC_018002:c1542767-1542504 [Sulfurospirillum barnesii SES-3]
ATGGCGCAAGTAAACATCAATATCCGCATGGATGAAACAGTCAAAAAACAAGCCGAAGAGCTTTTTAATGAGTTAGGGCT
TAACATGACCACAGCGTTTAACATGTTTGTTCGTCAAGCGCTCAACCGTGGTGGCATCCCTTTTGAAGTGGTGCGTAAAG
ATGCGTTTTATAGCCCGTACAATCAAGAAAAATTACGAGAATCCATCGCCAGTACCGACAAAACAGTAAAAAGCCTTGAT
GCGTTAGAAAAGCTAGCGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBI3XY30

Antitoxin

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Source
ID
Structure
AlphaFold DBI3XY31

References