Detailed information of TA system TA027898

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 937549..938078
• Replicon: chromosome
• Accession: NC_018002
• Organism: Sulfurospirillum barnesii SES-3

Toxin (Protein)

• Gene name: -
• Uniprot ID: I3XWD8
• Locus tag: SULBA_RS04775
• Protein ID: WP_014769141.1
• Coordinates: 937549..937800 (+)
• Length: 84 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: SULBA_RS04780
• Protein ID: WP_041671926.1
• Coordinates: 937806..938078 (+)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SULBA_RS04765	932977..933981	+	1005	WP_014769139.1	type I-B CRISPR-associated endonuclease Cas1	-
SULBA_RS04770	933978..934289	+	312	WP_014769140.1	CRISPR-associated endonuclease Cas2	-
SULBA_RS04775	937549..937800	+	252	WP_014769141.1	BrnT family toxin	Toxin
SULBA_RS04780	937806..938078	+	273	WP_041671926.1	hypothetical protein	Antitoxin
SULBA_RS04785	938112..938657	-	546	WP_014769143.1	hypothetical protein	-
SULBA_RS04790	938662..938976	-	315	WP_014769144.1	hypothetical protein	-
SULBA_RS04795	938998..939231	-	234	WP_014769145.1	hypothetical protein	-
SULBA_RS04800	939558..940406	+	849	WP_014769146.1	hypothetical protein	-
SULBA_RS04805	940484..940684	+	201	WP_014769147.1	hypothetical protein	-
SULBA_RS04810	940836..941168	+	333	WP_014769148.1	hypothetical protein	-
SULBA_RS12925	941165..941305	+	141	WP_014769149.1	hypothetical protein	-
SULBA_RS04815	941302..942270	+	969	WP_014769150.1	type II and III secretion system protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (4-79)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 9940.28 Da
• Isoelectric Point: 4.7330

>T27898 WP_014769141.1 NC_018002:937549-937800 [Sulfurospirillum barnesii SES-3]
MFEYDEAKSQANKEKHGIDFEEAQALWDNEYLVFKQVEINNEERFLLVGHIGELCYVAVFTMREDNIRIISVRRCRKNEK
EIV

Nucleotide

• Length: 252 bp

>T27898 NC_018002:937549-937800 [Sulfurospirillum barnesii SES-3]
ATGTTTGAATACGATGAAGCAAAGAGTCAAGCCAACAAAGAAAAACATGGAATTGACTTTGAAGAAGCTCAAGCTCTTTG
GGATAATGAATACTTGGTTTTTAAACAAGTTGAAATAAACAATGAAGAGCGTTTTTTACTGGTAGGTCATATTGGTGAAC
TTTGTTATGTGGCTGTCTTTACTATGCGTGAAGACAATATTCGCATTATCAGCGTGAGACGATGTCGAAAAAATGAAAAG
GAGATAGTATGA

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 10371.10 Da
• Isoelectric Point: 9.9418

>AT27898 WP_041671926.1 NC_018002:937806-938078 [Sulfurospirillum barnesii SES-3]
ISAEEFDRKFDNGEDILPYIDLSSKMTKSEFEKKLLSIKKVNVDLPSWAIASLDKEAKRMGVTRQSIIKMWLIQKLDDLN
LSRKSLKQVG

Nucleotide

• Length: 273 bp

>AT27898 NC_018002:937806-938078 [Sulfurospirillum barnesii SES-3]
ATATCAGCAGAAGAATTTGATAGAAAATTTGATAATGGTGAAGATATACTCCCTTATATTGATTTATCTTCTAAAATGAC
TAAAAGTGAATTTGAAAAAAAGTTATTGTCAATCAAAAAAGTAAATGTAGATTTGCCATCATGGGCGATTGCTTCTTTAG
ACAAAGAGGCTAAACGTATGGGTGTCACACGTCAGTCTATCATTAAAATGTGGCTCATTCAAAAGCTTGATGATTTAAAC
CTTAGTCGTAAATCTTTAAAACAAGTGGGATAA

Structures

Toxin

• AlphaFold DB: I3XWD8