Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1837896..1838041 Replicon chromosome
Accession NZ_CP123430
Organism Klebsiella pneumoniae strain SH22PE16

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1837932..1838034 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1837896..1838041 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QEZ34_RS08915 1833026..1835086 + 2061 WP_004151449.1 oligopeptidase B -
QEZ34_RS08920 1835090..1835749 - 660 WP_002911407.1 exodeoxyribonuclease X -
QEZ34_RS08925 1835828..1836058 - 231 WP_002911406.1 DNA polymerase III subunit theta -
QEZ34_RS08930 1836171..1836545 + 375 WP_004151448.1 CopC domain-containing protein YobA -
QEZ34_RS08935 1836549..1837418 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
QEZ34_RS08940 1837435..1837773 + 339 WP_002911404.1 YebY family protein -
- 1837896..1838041 - 146 - - Antitoxin
- 1837932..1838034 + 103 - - Toxin
QEZ34_RS08945 1838409..1838552 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
QEZ34_RS08950 1838657..1839625 - 969 WP_004151446.1 VirK/YbjX family protein -
QEZ34_RS08955 1839782..1840435 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
QEZ34_RS08960 1840432..1840623 - 192 WP_002911395.1 YebW family protein -
QEZ34_RS08965 1840721..1840960 - 240 WP_002911393.1 YebV family protein -
QEZ34_RS08970 1841076..1842509 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T278975 NZ_CP123430:1837932-1838034 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT278975 NZ_CP123430:c1838041-1837896 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References