278970

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 2917637..2918199 Replicon chromosome
Accession NZ_CP123381
Organism Gordonia sp. SMJS1

Toxin (Protein)


Gene name relE Uniprot ID A0A6G7W718
Locus tag QAD21_RS13385 Protein ID WP_055477308.1
Coordinates 2917637..2917927 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A6G7W6R5
Locus tag QAD21_RS13390 Protein ID WP_055477309.1
Coordinates 2917924..2918199 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QAD21_RS13365 (QAD21_13365) 2913588..2915648 + 2061 WP_068970440.1 DEAD/DEAH box helicase family protein -
QAD21_RS13370 (QAD21_13370) 2915683..2915922 + 240 WP_055477305.1 hypothetical protein -
QAD21_RS13375 (QAD21_13375) 2916511..2916744 + 234 WP_055477307.1 hypothetical protein -
QAD21_RS13380 (QAD21_13380) 2917412..2917618 + 207 WP_055477311.1 hypothetical protein -
QAD21_RS13385 (QAD21_13385) 2917637..2917927 - 291 WP_055477308.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QAD21_RS13390 (QAD21_13390) 2917924..2918199 - 276 WP_055477309.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QAD21_RS13395 (QAD21_13395) 2918319..2918939 - 621 WP_223258858.1 TetR/AcrR family transcriptional regulator -
QAD21_RS13400 (QAD21_13400) 2918936..2919463 - 528 WP_065631669.1 GNAT family N-acetyltransferase -
QAD21_RS13405 (QAD21_13405) 2919871..2920632 + 762 WP_139104661.1 hypothetical protein -
QAD21_RS13410 (QAD21_13410) 2920687..2920992 + 306 WP_280359662.1 hypothetical protein -
QAD21_RS13415 (QAD21_13415) 2921044..2921424 - 381 WP_065631666.1 SRPBCC family protein -
QAD21_RS13420 (QAD21_13420) 2921573..2922478 - 906 WP_065631665.1 RNA polymerase sigma-70 factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(14-94)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10938.40 Da        Isoelectric Point: 9.7360

>T278970 WP_055477308.1 NZ_CP123381:c2917927-2917637 [Gordonia sp. SMJS1]
MSDAPTDSSAPYRVEVASPARRDLQRLPSRIVHAVIEFISGPLAENPHRLSKPLRDDLADLHSARRGDYRILLRIDDPNH
TIVIVRIDHRAHAYRT

Download         Length: 291 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9718.86 Da        Isoelectric Point: 4.3809

>AT278970 WP_055477309.1 NZ_CP123381:c2918199-2917924 [Gordonia sp. SMJS1]
MTTVPLGEAKDKLSALVDSAESTHDIITITKHGKPAAVLMSADDLESLHETIYWLSRAGVRDDVATADAEYAAGETVSID
DLRAEHGMPPK

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6G7W718

Antitoxin

Source ID Structure
AlphaFold DB A0A6G7W6R5

References