278969

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PHD(antitoxin)
Location 1266194..1266867 Replicon chromosome
Accession NZ_CP123381
Organism Gordonia sp. SMJS1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QAD21_RS05770 Protein ID WP_280360757.1
Coordinates 1266463..1266867 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QAD21_RS05765 Protein ID WP_280360756.1
Coordinates 1266194..1266466 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QAD21_RS05745 (QAD21_05745) 1261298..1261879 - 582 WP_058251656.1 TetR/AcrR family transcriptional regulator -
QAD21_RS05750 (QAD21_05750) 1261954..1262935 + 982 Protein_1129 LLM class F420-dependent oxidoreductase -
QAD21_RS05755 (QAD21_05755) 1263118..1264284 - 1167 WP_280360752.1 pyridoxal phosphate-dependent aminotransferase -
QAD21_RS05760 (QAD21_05760) 1264382..1266061 + 1680 WP_280360754.1 protein kinase -
QAD21_RS05765 (QAD21_05765) 1266194..1266466 + 273 WP_280360756.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QAD21_RS05770 (QAD21_05770) 1266463..1266867 + 405 WP_280360757.1 type II toxin-antitoxin system VapC family toxin Toxin
QAD21_RS05775 (QAD21_05775) 1266869..1268545 - 1677 WP_065631752.1 DEAD/DEAH box helicase -
QAD21_RS05780 (QAD21_05780) 1268612..1269541 - 930 WP_280360780.1 oxygenase MpaB family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-116)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-46)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14170.42 Da        Isoelectric Point: 5.1057

>T278969 WP_280360757.1 NZ_CP123381:1266463-1266867 [Gordonia sp. SMJS1]
MIYLDTAAMVKLVVREAETAQLIEWLALHPGVPTVTSALGRVELMRTALRDGSPGLHERARVLLDALDVIPLSVTVIDIA
ESIGPSSLRSLDALHLASASVIRAEMSAFVAYDHRLLAGASTLGYPTVAPGAES

Download         Length: 405 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9863.29 Da        Isoelectric Point: 10.6803

>AT278969 WP_280360756.1 NZ_CP123381:1266194-1266466 [Gordonia sp. SMJS1]
MRTIGIRELRQHASRYLAQVEAGEELAITNRGRTVARLVPVSAGERSRDALIEAGILLPARRAGGITGLHPETLPARALT
EVLDQVREDR

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References