Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1886975..1887209 | Replicon | chromosome |
| Accession | NZ_CP123365 | ||
| Organism | Shigella flexneri strain MMGSG_23 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1886976..1887079 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1886975..1887209 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PFB08_RS09680 | 1882421..1882888 | - | 468 | Protein_1897 | DNA-binding transcriptional regulator PgrR | - |
| PFB08_RS09685 | 1882952..1883262 | + | 311 | Protein_1898 | transposase | - |
| PFB08_RS09690 | 1883305..1884500 | - | 1196 | Protein_1899 | IS3 family transposase | - |
| PFB08_RS09695 | 1884555..1885403 | + | 849 | Protein_1900 | IS3-like element IS600 family transposase | - |
| PFB08_RS09700 | 1885520..1885801 | + | 282 | WP_005127484.1 | excisionase | - |
| PFB08_RS09705 | 1885767..1886844 | + | 1078 | Protein_1902 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 1886975..1887209 | + | 235 | - | - | Antitoxin |
| - | 1886976..1887079 | - | 104 | - | - | Toxin |
| PFB08_RS09710 | 1887237..1887578 | - | 342 | WP_000976476.1 | YebY family protein | - |
| PFB08_RS09715 | 1887591..1888463 | - | 873 | Protein_1904 | copper homeostasis membrane protein CopD | - |
| PFB08_RS09720 | 1888467..1888841 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| PFB08_RS09725 | 1888980..1889210 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| PFB08_RS09730 | 1889312..1889968 | + | 657 | Protein_1907 | carbon-nitrogen hydrolase family protein YobB | - |
| PFB08_RS09735 | 1889992..1890654 | + | 663 | WP_000944268.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | ipaH9.8 | 1878093..1945707 | 67614 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T278951 NZ_CP123365:c1887079-1886976 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT278951 NZ_CP123365:1886975-1887209 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
