Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 281794..282464 Replicon plasmid unnamed
Accession NZ_CP123353
Organism Agrobacterium pusense strain GV2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QE155_RS24030 Protein ID WP_006699040.1
Coordinates 281794..282213 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QE155_RS24035 Protein ID WP_280171387.1
Coordinates 282210..282464 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QE155_RS24015 278058..278312 + 255 WP_280171384.1 DUF6117 family protein -
QE155_RS24020 279037..280083 + 1047 WP_280171385.1 toprim domain-containing protein -
QE155_RS24025 280413..281354 + 942 WP_280171386.1 DUF2493 domain-containing protein -
QE155_RS24030 281794..282213 - 420 WP_006699040.1 type II toxin-antitoxin system VapC family toxin Toxin
QE155_RS24035 282210..282464 - 255 WP_280171387.1 plasmid stabilization protein Antitoxin
QE155_RS24040 282620..282817 - 198 WP_280171388.1 hypothetical protein -
QE155_RS24045 282898..283422 - 525 WP_280171389.1 RES domain-containing protein -
QE155_RS24050 283419..283904 - 486 WP_280171390.1 DUF2384 domain-containing protein -
QE155_RS24055 284309..284632 + 324 WP_006699035.1 DUF736 family protein -
QE155_RS24060 284691..285110 + 420 WP_280171391.1 hypothetical protein -
QE155_RS24065 285088..285366 - 279 WP_045535232.1 HU family DNA-binding protein -
QE155_RS24070 286108..286392 + 285 Protein_271 site-specific integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..448874 448874


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15050.15 Da        Isoelectric Point: 4.8728

>T278940 WP_006699040.1 NZ_CP123353:c282213-281794 [Agrobacterium pusense]
MILLDTNVVSETMKPFPSQMVQRWLDEQAAETLHLSSITIAEAMFGIRTMPDGQRKQRLAEALDVWIGLFEGRILPFDLD
AAKHYANLGSSARASGKGFPTPDGYIAAIAASKGFAVATRDASAFHAAGLEVIDPWTAE

Download         Length: 420 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9376.62 Da        Isoelectric Point: 6.7270

>AT278940 WP_280171387.1 NZ_CP123353:c282464-282210 [Agrobacterium pusense]
MPAVTIRNIPEETHRAIKIRAAQHGRSAEAEMRDILETAVRPATRLRLGTALAEASRRIGLTNEDVDALEQTFDRTPAHP
MSFE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References