Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 739255..739886 Replicon chromosome
Accession NZ_CP123351
Organism Agrobacterium pusense strain GV2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QE155_RS03645 Protein ID WP_035207667.1
Coordinates 739488..739886 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QE155_RS03640 Protein ID WP_035207666.1
Coordinates 739255..739488 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QE155_RS03620 734656..735918 + 1263 WP_004441057.1 beta-ketoacyl-ACP synthase II -
QE155_RS03625 736281..737501 + 1221 WP_004441060.1 endolytic transglycosylase MltG -
QE155_RS03630 737573..738460 + 888 WP_006700159.1 YicC/YloC family endoribonuclease -
QE155_RS03635 738465..739127 + 663 WP_004441063.1 guanylate kinase -
QE155_RS03640 739255..739488 + 234 WP_035207666.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
QE155_RS03645 739488..739886 + 399 WP_035207667.1 type II toxin-antitoxin system VapC family toxin Toxin
QE155_RS03650 739902..740732 - 831 WP_035207668.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -
QE155_RS03655 740732..741754 - 1023 WP_077987860.1 4-hydroxythreonine-4-phosphate dehydrogenase PdxA -
QE155_RS03660 741781..742728 - 948 WP_006700162.1 peptidylprolyl isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-56)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14855.11 Da        Isoelectric Point: 7.1886

>T278937 WP_035207667.1 NZ_CP123351:739488-739886 [Agrobacterium pusense]
MLRYMLDTNICIYVMKTYPTDLRDKFNSLADELCISSITLGELCYGAEKSARRRENLGAIENFTARLEVLPFADKAASHY
GQIRAELARAGTPCGVHDMQIGGHARSEGLIVVTNNMREFVRMPGLRVENWV

Download         Length: 399 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8768.97 Da        Isoelectric Point: 5.8064

>AT278937 WP_035207666.1 NZ_CP123351:739255-739488 [Agrobacterium pusense]
MATSTVFTSNRSQAVRLPKTVAFPDDVHKVEILKVGLTRIIVPYGKRWDDLFLSGPRATDDFMSSREEPPLEERDSF

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References