278935

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 322794..323268 Replicon chromosome
Accession NZ_CP123351
Organism Agrobacterium pusense strain GV2

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag QE155_RS01525 Protein ID WP_077986677.1
Coordinates 322794..323051 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID A0A1S7Q717
Locus tag QE155_RS01530 Protein ID WP_004440186.1
Coordinates 323035..323268 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QE155_RS01490 317882..318511 + 630 WP_004440176.1 DNA-3-methyladenine glycosylase I -
QE155_RS01495 318508..318951 + 444 WP_004440178.1 hypothetical protein -
QE155_RS01500 318966..320009 - 1044 WP_092651130.1 YeiH family protein -
QE155_RS01505 320091..321008 + 918 WP_077986674.1 LysR substrate-binding domain-containing protein -
QE155_RS01510 321154..321528 - 375 WP_004440183.1 DUF305 domain-containing protein -
QE155_RS01515 321586..321969 - 384 WP_223215375.1 hypothetical protein -
QE155_RS01520 322011..322775 - 765 WP_077986676.1 hypothetical protein -
QE155_RS01525 322794..323051 - 258 WP_077986677.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QE155_RS01530 323035..323268 - 234 WP_004440186.1 DUF6290 family protein Antitoxin
QE155_RS01535 323502..325025 + 1524 WP_077986678.1 histidine--tRNA ligase -
QE155_RS01540 325030..325398 + 369 WP_006699502.1 VOC family protein -
QE155_RS01545 325415..326539 + 1125 WP_077986679.1 ATP phosphoribosyltransferase regulatory subunit -
QE155_RS01550 326536..327228 + 693 WP_077986680.1 ATP phosphoribosyltransferase -
QE155_RS01555 327291..327736 - 446 Protein_304 DoxX family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-85)

Antitoxin

Protein of unknown function DUF6290

(6-73)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10002.51 Da        Isoelectric Point: 9.6257

>T278935 WP_077986677.1 NZ_CP123351:c323051-322794 [Agrobacterium pusense]
MIWKIEFQHRAVKELEKLAKQDANRIVSFLADRVVQNENPRQTGAALQGSELGNYWRYRVGDYRIICDIQDHKLVVLVVE
IGHRR

Download         Length: 258 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 9225.31 Da        Isoelectric Point: 4.7359

>AT278935 WP_004440186.1 NZ_CP123351:c323268-323035 [Agrobacterium pusense]
MSKQTAIRLPDETYERLKALSERTGRTSAYYIREAIEKHIEDMEDLYLAEEATRRRIANNERTYTLEEVMRNLDLEN

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1S7Q717

References