Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) abiEi-abiEii/AbiEii-AbiEi
Location 242070..243537 Replicon chromosome
Accession NZ_CP123306
Organism Mycoplasmopsis bovis strain 16DD0001

Toxin (Protein)


Gene name abiEi Uniprot ID Q932V7
Locus tag QEP42_RS01135 Protein ID WP_041309184.1
Coordinates 242677..243537 (+) Length 287 a.a.

Antitoxin (Protein)


Gene name abiEii Uniprot ID Q934C3
Locus tag QEP42_RS01130 Protein ID WP_013456322.1
Coordinates 242070..242684 (+) Length 205 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QEP42_RS01095 237528..237599 + 72 WP_235670904.1 variable surface lipoprotein -
QEP42_RS01100 237604..237834 + 231 WP_280124641.1 hypothetical protein -
QEP42_RS01105 237828..238160 + 333 WP_280124642.1 hypothetical protein -
QEP42_RS01110 238325..238933 + 609 WP_280124643.1 variable surface lipoprotein -
QEP42_RS01115 239192..239827 - 636 WP_143823050.1 variable surface lipoprotein -
QEP42_RS01120 239993..240811 - 819 WP_238562475.1 variable surface lipoprotein -
QEP42_RS01125 240997..241887 - 891 WP_075271150.1 variable surface lipoprotein -
QEP42_RS01130 242070..242684 + 615 WP_013456322.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
QEP42_RS01135 242677..243537 + 861 WP_041309184.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
QEP42_RS01140 243657..244547 + 891 WP_075271150.1 variable surface lipoprotein -
QEP42_RS01145 244735..245385 + 651 WP_214461189.1 variable surface lipoprotein -
QEP42_RS01150 245550..246275 + 726 WP_075271933.1 variable surface lipoprotein -
QEP42_RS01155 246318..246893 - 576 WP_075271397.1 variable surface lipoprotein -
QEP42_RS01160 247042..248133 - 1092 WP_075271791.1 variable surface lipoprotein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(33-234)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(13-59)


Sequences

Toxin        


Download         Length: 287 a.a.        Molecular weight: 33281.35 Da        Isoelectric Point: 7.2878

>T278933 WP_041309184.1 NZ_CP123306:242677-243537 [Mycoplasmopsis bovis]
MNKNKLISLCHKTADENNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNADDIDGIRYHILKYTDIRKEHKYSGINISVLCQIENIKQVISIDIASGDVITPKEIVYEYKSIFSNQD
FSILAYNIETMLSEKLETIFSFGHLNTRFKDFYDVYVIYTFKKKDIDINRLKDACYNTFKNRNSEFNIQQLLELITNIAF
NPLMNERKKYISQIANQQEIDFKAITNSIIELLELIKVNELTNND

Download         Length: 861 bp

Antitoxin


Download         Length: 205 a.a.        Molecular weight: 24143.83 Da        Isoelectric Point: 9.7617

>AT278933 WP_013456322.1 NZ_CP123306:242070-242684 [Mycoplasmopsis bovis]
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMITKGVLIRRAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE

Download         Length: 615 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q932V7

Antitoxin

Source ID Structure
AlphaFold DB Q934C3

References