Detailed information of TA system
Overview
TA module
| Type | IV | Classification (family/domain) | abiEi-abiEii/AbiEii-AbiEi |
| Location | 285736..287203 | Replicon | chromosome |
| Accession | NZ_CP123305 | ||
| Organism | Mycoplasmopsis bovis strain 15DL0124 | ||
Toxin (Protein)
| Gene name | abiEi | Uniprot ID | A0A2N8U3K6 |
| Locus tag | QEP47_RS01235 | Protein ID | WP_014829995.1 |
| Coordinates | 285736..286596 (-) | Length | 287 a.a. |
Antitoxin (Protein)
| Gene name | abiEii | Uniprot ID | Q934C3 |
| Locus tag | QEP47_RS01240 | Protein ID | WP_013456322.1 |
| Coordinates | 286589..287203 (-) | Length | 205 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QEP47_RS01215 | 281560..282138 | + | 579 | WP_280125093.1 | variable surface lipoprotein | - |
| QEP47_RS01220 | 282146..283579 | - | 1434 | WP_101456648.1 | transposase | - |
| QEP47_RS01225 | 284109..284642 | - | 534 | WP_280125094.1 | variable surface lipoprotein | - |
| QEP47_RS01230 | 284818..285615 | - | 798 | WP_280125095.1 | variable surface lipoprotein | - |
| QEP47_RS01235 | 285736..286596 | - | 861 | WP_014829995.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| QEP47_RS01240 | 286589..287203 | - | 615 | WP_013456322.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
| QEP47_RS01245 | 287386..288018 | + | 633 | WP_280125096.1 | variable surface lipoprotein | - |
| QEP47_RS01250 | 288015..288185 | - | 171 | WP_280125097.1 | hypothetical protein | - |
| QEP47_RS01255 | 288335..289003 | + | 669 | WP_280125098.1 | variable surface lipoprotein | - |
| QEP47_RS01260 | 289274..289879 | - | 606 | WP_226084206.1 | variable surface lipoprotein | - |
| QEP47_RS01265 | 290064..290270 | - | 207 | WP_214472638.1 | hypothetical protein | - |
| QEP47_RS01270 | 291607..291711 | - | 105 | Protein_240 | variable surface lipoprotein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 287 a.a. Molecular weight: 33280.36 Da Isoelectric Point: 7.7731
>T278932 WP_014829995.1 NZ_CP123305:c286596-285736 [Mycoplasmopsis bovis]
MNKNKLISLCHKTADQNNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNADDIDGIRYHILKYTDIRKEHKYSGINISVLCQIENIKQVISIDIASGDVITPKEIVYEYKSIFSNQD
FSILAYNIETMLSEKLETIFSFGHLNTRFKDFYDVYVIYTFKKKDIDINRLKDACYNTFKNRNSEFNIQQLLELITNIAF
NPLMNERKKYISQIANQQEIDFKAITNSIIELLELIKVNELTNND
MNKNKLISLCHKTADQNNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNADDIDGIRYHILKYTDIRKEHKYSGINISVLCQIENIKQVISIDIASGDVITPKEIVYEYKSIFSNQD
FSILAYNIETMLSEKLETIFSFGHLNTRFKDFYDVYVIYTFKKKDIDINRLKDACYNTFKNRNSEFNIQQLLELITNIAF
NPLMNERKKYISQIANQQEIDFKAITNSIIELLELIKVNELTNND
Download Length: 861 bp
Antitoxin
Download Length: 205 a.a. Molecular weight: 24143.83 Da Isoelectric Point: 9.7617
>AT278932 WP_013456322.1 NZ_CP123305:c287203-286589 [Mycoplasmopsis bovis]
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMITKGVLIRRAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMITKGVLIRRAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE
Download Length: 615 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A2N8U3K6 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | Q934C3 |