Detailed information of TA system
Overview
TA module
| Type | IV | Classification (family/domain) | abiEi-abiEii/AbiEii-AbiEi |
| Location | 234172..235639 | Replicon | chromosome |
| Accession | NZ_CP123303 | ||
| Organism | Mycoplasmopsis bovis strain 15DD0250 | ||
Toxin (Protein)
| Gene name | abiEi | Uniprot ID | Q932V7 |
| Locus tag | QEP48_RS01050 | Protein ID | WP_041309184.1 |
| Coordinates | 234779..235639 (+) | Length | 287 a.a. |
Antitoxin (Protein)
| Gene name | abiEii | Uniprot ID | Q934C3 |
| Locus tag | QEP48_RS01045 | Protein ID | WP_013456322.1 |
| Coordinates | 234172..234786 (+) | Length | 205 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QEP48_RS01025 | 229813..230841 | + | 1029 | WP_238562546.1 | IS30-like element ISMbov1 family transposase | - |
| QEP48_RS01030 | 231052..232059 | + | 1008 | WP_075270934.1 | ECF transporter S component | - |
| QEP48_RS01035 | 232607..232957 | + | 351 | Protein_197 | variable surface lipoprotein | - |
| QEP48_RS01040 | 233225..233989 | - | 765 | WP_075270933.1 | variable surface lipoprotein | - |
| QEP48_RS01045 | 234172..234786 | + | 615 | WP_013456322.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
| QEP48_RS01050 | 234779..235639 | + | 861 | WP_041309184.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| QEP48_RS01055 | 235759..236850 | + | 1092 | WP_075271791.1 | variable surface lipoprotein | - |
| QEP48_RS01060 | 236999..237583 | + | 585 | WP_075271399.1 | variable surface lipoprotein | - |
| QEP48_RS01065 | 237842..238441 | - | 600 | WP_280124779.1 | variable surface lipoprotein | - |
| QEP48_RS01070 | 238658..238813 | + | 156 | WP_180370284.1 | hypothetical protein | - |
| QEP48_RS01075 | 239026..240440 | - | 1415 | Protein_205 | IS1634-like element ISMbov2 family transposase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | flank | IS/Tn | - | - | 229723..230841 | 1118 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 287 a.a. Molecular weight: 33281.35 Da Isoelectric Point: 7.2878
>T278930 WP_041309184.1 NZ_CP123303:234779-235639 [Mycoplasmopsis bovis]
MNKNKLISLCHKTADENNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNADDIDGIRYHILKYTDIRKEHKYSGINISVLCQIENIKQVISIDIASGDVITPKEIVYEYKSIFSNQD
FSILAYNIETMLSEKLETIFSFGHLNTRFKDFYDVYVIYTFKKKDIDINRLKDACYNTFKNRNSEFNIQQLLELITNIAF
NPLMNERKKYISQIANQQEIDFKAITNSIIELLELIKVNELTNND
MNKNKLISLCHKTADENNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNADDIDGIRYHILKYTDIRKEHKYSGINISVLCQIENIKQVISIDIASGDVITPKEIVYEYKSIFSNQD
FSILAYNIETMLSEKLETIFSFGHLNTRFKDFYDVYVIYTFKKKDIDINRLKDACYNTFKNRNSEFNIQQLLELITNIAF
NPLMNERKKYISQIANQQEIDFKAITNSIIELLELIKVNELTNND
Download Length: 861 bp
Antitoxin
Download Length: 205 a.a. Molecular weight: 24143.83 Da Isoelectric Point: 9.7617
>AT278930 WP_013456322.1 NZ_CP123303:234172-234786 [Mycoplasmopsis bovis]
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMITKGVLIRRAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMITKGVLIRRAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE
Download Length: 615 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|