Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | abiEi-abiEii/AbiEii-AbiEi |
Location | 814145..815612 | Replicon | chromosome |
Accession | NZ_CP123302 | ||
Organism | Mycoplasmopsis bovis strain 15DD0249 |
Toxin (Protein)
Gene name | abiEi | Uniprot ID | A0A2N8U3K6 |
Locus tag | QEP32_RS03510 | Protein ID | WP_014829995.1 |
Coordinates | 814752..815612 (+) | Length | 287 a.a. |
Antitoxin (Protein)
Gene name | abiEii | Uniprot ID | Q934C3 |
Locus tag | QEP32_RS03505 | Protein ID | WP_013456322.1 |
Coordinates | 814145..814759 (+) | Length | 205 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QEP32_RS03480 | 809826..810855 | - | 1030 | Protein_660 | IS30-like element ISMbov1 family transposase | - |
QEP32_RS03490 | 811479..812228 | - | 750 | WP_013456123.1 | tyrosine-type recombinase/integrase | - |
QEP32_RS03495 | 812514..813089 | + | 576 | WP_280124673.1 | variable surface lipoprotein | - |
QEP32_RS03500 | 813132..813962 | - | 831 | Protein_663 | variable surface lipoprotein | - |
QEP32_RS03505 | 814145..814759 | + | 615 | WP_013456322.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
QEP32_RS03510 | 814752..815612 | + | 861 | WP_014829995.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
QEP32_RS03515 | 815733..816458 | + | 726 | WP_280124674.1 | variable surface lipoprotein | - |
QEP32_RS03520 | 816634..817530 | + | 897 | WP_280124675.1 | variable surface lipoprotein | - |
QEP32_RS03525 | 817689..818321 | + | 633 | WP_280124676.1 | variable surface lipoprotein | - |
QEP32_RS03530 | 818580..819188 | - | 609 | WP_115276525.1 | variable surface lipoprotein | - |
QEP32_RS03535 | 819364..819966 | - | 603 | WP_280124677.1 | variable surface lipoprotein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 287 a.a. Molecular weight: 33280.36 Da Isoelectric Point: 7.7731
>T278929 WP_014829995.1 NZ_CP123302:814752-815612 [Mycoplasmopsis bovis]
MNKNKLISLCHKTADQNNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNADDIDGIRYHILKYTDIRKEHKYSGINISVLCQIENIKQVISIDIASGDVITPKEIVYEYKSIFSNQD
FSILAYNIETMLSEKLETIFSFGHLNTRFKDFYDVYVIYTFKKKDIDINRLKDACYNTFKNRNSEFNIQQLLELITNIAF
NPLMNERKKYISQIANQQEIDFKAITNSIIELLELIKVNELTNND
MNKNKLISLCHKTADQNNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNADDIDGIRYHILKYTDIRKEHKYSGINISVLCQIENIKQVISIDIASGDVITPKEIVYEYKSIFSNQD
FSILAYNIETMLSEKLETIFSFGHLNTRFKDFYDVYVIYTFKKKDIDINRLKDACYNTFKNRNSEFNIQQLLELITNIAF
NPLMNERKKYISQIANQQEIDFKAITNSIIELLELIKVNELTNND
Download Length: 861 bp
Antitoxin
Download Length: 205 a.a. Molecular weight: 24143.83 Da Isoelectric Point: 9.7617
>AT278929 WP_013456322.1 NZ_CP123302:814145-814759 [Mycoplasmopsis bovis]
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMITKGVLIRRAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMITKGVLIRRAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE
Download Length: 615 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2N8U3K6 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | Q934C3 |