Detailed information of TA system
Overview
TA module
| Type | IV | Classification (family/domain) | abiEi-abiEii/AbiEii-AbiEi |
| Location | 350613..352080 | Replicon | chromosome |
| Accession | NZ_CP123301 | ||
| Organism | Mycoplasmopsis bovis strain 15DD0240 | ||
Toxin (Protein)
| Gene name | abiEi | Uniprot ID | Q932V7 |
| Locus tag | QEP52_RS01600 | Protein ID | WP_041309184.1 |
| Coordinates | 350613..351473 (-) | Length | 287 a.a. |
Antitoxin (Protein)
| Gene name | abiEii | Uniprot ID | Q934C3 |
| Locus tag | QEP52_RS01605 | Protein ID | WP_013456322.1 |
| Coordinates | 351466..352080 (-) | Length | 205 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QEP52_RS01565 | 345614..346291 | + | 678 | WP_280124593.1 | variable surface lipoprotein | - |
| QEP52_RS01570 | 346334..347128 | - | 795 | WP_280124594.1 | variable surface lipoprotein | - |
| QEP52_RS01575 | 347398..348642 | - | 1245 | Protein_294 | IS3 family transposase | - |
| QEP52_RS01580 | 349159..349305 | + | 147 | WP_280124595.1 | variable surface lipoprotein | - |
| QEP52_RS01585 | 349235..349657 | + | 423 | WP_280124596.1 | hypothetical protein | - |
| QEP52_RS01590 | 349749..350420 | - | 672 | WP_280124614.1 | hypothetical protein | - |
| QEP52_RS01595 | 350446..350493 | - | 48 | Protein_298 | variable surface lipoprotein | - |
| QEP52_RS01600 | 350613..351473 | - | 861 | WP_041309184.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| QEP52_RS01605 | 351466..352080 | - | 615 | WP_013456322.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
| QEP52_RS01610 | 352263..352934 | + | 672 | WP_280124597.1 | variable surface lipoprotein | - |
| QEP52_RS01615 | 353079..353705 | + | 627 | WP_280124598.1 | variable surface lipoprotein | - |
| QEP52_RS01620 | 354055..355656 | - | 1602 | WP_078086164.1 | IS1634-like element ISMbov3 family transposase | - |
| QEP52_RS01625 | 356144..356830 | - | 687 | WP_280124599.1 | variable surface lipoprotein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 287 a.a. Molecular weight: 33281.35 Da Isoelectric Point: 7.2878
>T278928 WP_041309184.1 NZ_CP123301:c351473-350613 [Mycoplasmopsis bovis]
MNKNKLISLCHKTADENNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNADDIDGIRYHILKYTDIRKEHKYSGINISVLCQIENIKQVISIDIASGDVITPKEIVYEYKSIFSNQD
FSILAYNIETMLSEKLETIFSFGHLNTRFKDFYDVYVIYTFKKKDIDINRLKDACYNTFKNRNSEFNIQQLLELITNIAF
NPLMNERKKYISQIANQQEIDFKAITNSIIELLELIKVNELTNND
MNKNKLISLCHKTADENNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNADDIDGIRYHILKYTDIRKEHKYSGINISVLCQIENIKQVISIDIASGDVITPKEIVYEYKSIFSNQD
FSILAYNIETMLSEKLETIFSFGHLNTRFKDFYDVYVIYTFKKKDIDINRLKDACYNTFKNRNSEFNIQQLLELITNIAF
NPLMNERKKYISQIANQQEIDFKAITNSIIELLELIKVNELTNND
Download Length: 861 bp
Antitoxin
Download Length: 205 a.a. Molecular weight: 24143.83 Da Isoelectric Point: 9.7617
>AT278928 WP_013456322.1 NZ_CP123301:c352080-351466 [Mycoplasmopsis bovis]
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMITKGVLIRRAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMITKGVLIRRAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE
Download Length: 615 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|