Detailed information of TA system
Overview
TA module
| Type | IV | Classification (family/domain) | abiEi-abiEii/AbiEii-AbiEi |
| Location | 248577..250044 | Replicon | chromosome |
| Accession | NZ_CP123298 | ||
| Organism | Mycoplasmopsis bovis strain 15DD0233 | ||
Toxin (Protein)
| Gene name | abiEi | Uniprot ID | Q932V7 |
| Locus tag | QEP44_RS01145 | Protein ID | WP_041309184.1 |
| Coordinates | 249184..250044 (+) | Length | 287 a.a. |
Antitoxin (Protein)
| Gene name | abiEii | Uniprot ID | Q934C3 |
| Locus tag | QEP44_RS01140 | Protein ID | WP_013456322.1 |
| Coordinates | 248577..249191 (+) | Length | 205 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QEP44_RS01115 | 243755..244783 | + | 1029 | WP_078086175.1 | IS30-like element ISMbov1 family transposase | - |
| QEP44_RS01120 | 245207..245761 | + | 555 | WP_280124972.1 | variable surface lipoprotein | - |
| QEP44_RS01125 | 245937..246701 | + | 765 | WP_075270933.1 | variable surface lipoprotein | - |
| QEP44_RS01130 | 246969..247319 | - | 351 | Protein_216 | variable surface lipoprotein | - |
| QEP44_RS01135 | 247504..248394 | - | 891 | WP_075271150.1 | variable surface lipoprotein | - |
| QEP44_RS01140 | 248577..249191 | + | 615 | WP_013456322.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
| QEP44_RS01145 | 249184..250044 | + | 861 | WP_041309184.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| QEP44_RS01150 | 250164..251054 | + | 891 | WP_075271150.1 | variable surface lipoprotein | - |
| QEP44_RS01155 | 251242..251892 | + | 651 | WP_214461189.1 | variable surface lipoprotein | - |
| QEP44_RS01160 | 252056..252781 | + | 726 | WP_075271933.1 | variable surface lipoprotein | - |
| QEP44_RS01165 | 252824..253399 | - | 576 | WP_075271397.1 | variable surface lipoprotein | - |
| QEP44_RS01170 | 253548..254639 | - | 1092 | WP_075271791.1 | variable surface lipoprotein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 287 a.a. Molecular weight: 33281.35 Da Isoelectric Point: 7.2878
>T278925 WP_041309184.1 NZ_CP123298:249184-250044 [Mycoplasmopsis bovis]
MNKNKLISLCHKTADENNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNADDIDGIRYHILKYTDIRKEHKYSGINISVLCQIENIKQVISIDIASGDVITPKEIVYEYKSIFSNQD
FSILAYNIETMLSEKLETIFSFGHLNTRFKDFYDVYVIYTFKKKDIDINRLKDACYNTFKNRNSEFNIQQLLELITNIAF
NPLMNERKKYISQIANQQEIDFKAITNSIIELLELIKVNELTNND
MNKNKLISLCHKTADENNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNADDIDGIRYHILKYTDIRKEHKYSGINISVLCQIENIKQVISIDIASGDVITPKEIVYEYKSIFSNQD
FSILAYNIETMLSEKLETIFSFGHLNTRFKDFYDVYVIYTFKKKDIDINRLKDACYNTFKNRNSEFNIQQLLELITNIAF
NPLMNERKKYISQIANQQEIDFKAITNSIIELLELIKVNELTNND
Download Length: 861 bp
Antitoxin
Download Length: 205 a.a. Molecular weight: 24143.83 Da Isoelectric Point: 9.7617
>AT278925 WP_013456322.1 NZ_CP123298:248577-249191 [Mycoplasmopsis bovis]
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMITKGVLIRRAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMITKGVLIRRAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE
Download Length: 615 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|