Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) abiEi-abiEii/AbiEii-AbiEi
Location 945169..946636 Replicon chromosome
Accession NZ_CP123293
Organism Mycoplasmopsis bovis strain 15DD0160

Toxin (Protein)


Gene name abiEi Uniprot ID A0A2N8U3K6
Locus tag QEP41_RS04150 Protein ID WP_014829995.1
Coordinates 945776..946636 (+) Length 287 a.a.

Antitoxin (Protein)


Gene name abiEii Uniprot ID Q934C3
Locus tag QEP41_RS04145 Protein ID WP_013456322.1
Coordinates 945169..945783 (+) Length 205 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QEP41_RS04125 941409..942086 + 678 WP_280135631.1 variable surface lipoprotein -
QEP41_RS04130 942345..943214 - 870 WP_280135632.1 variable surface lipoprotein -
QEP41_RS04135 943390..944208 - 819 WP_280135633.1 variable surface lipoprotein -
QEP41_RS04140 944384..944986 - 603 WP_115306019.1 variable surface lipoprotein -
QEP41_RS04145 945169..945783 + 615 WP_013456322.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
QEP41_RS04150 945776..946636 + 861 WP_014829995.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
QEP41_RS04155 946756..947388 + 633 WP_226084202.1 variable surface lipoprotein -
QEP41_RS04160 947385..947555 - 171 WP_226088646.1 hypothetical protein -
QEP41_RS04165 947705..948469 + 765 WP_280135634.1 variable surface lipoprotein -
QEP41_RS04170 948512..949603 - 1092 WP_099620147.1 variable surface lipoprotein -
QEP41_RS04175 949779..950522 - 744 WP_280135635.1 variable surface lipoprotein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(33-234)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(13-59)


Sequences

Toxin        


Download         Length: 287 a.a.        Molecular weight: 33280.36 Da        Isoelectric Point: 7.7731

>T278921 WP_014829995.1 NZ_CP123293:945776-946636 [Mycoplasmopsis bovis]
MNKNKLISLCHKTADQNNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNADDIDGIRYHILKYTDIRKEHKYSGINISVLCQIENIKQVISIDIASGDVITPKEIVYEYKSIFSNQD
FSILAYNIETMLSEKLETIFSFGHLNTRFKDFYDVYVIYTFKKKDIDINRLKDACYNTFKNRNSEFNIQQLLELITNIAF
NPLMNERKKYISQIANQQEIDFKAITNSIIELLELIKVNELTNND

Download         Length: 861 bp

Antitoxin


Download         Length: 205 a.a.        Molecular weight: 24143.83 Da        Isoelectric Point: 9.7617

>AT278921 WP_013456322.1 NZ_CP123293:945169-945783 [Mycoplasmopsis bovis]
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMITKGVLIRRAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE

Download         Length: 615 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2N8U3K6

Antitoxin

Source ID Structure
AlphaFold DB Q934C3

References