278919

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) abiEi-abiEii/AbiEii-AbiEi
Location 539954..541421 Replicon chromosome
Accession NZ_CP123290
Organism Mycoplasmopsis bovis strain 15DD0161

Toxin (Protein)


Gene name abiEi Uniprot ID A0A2N8U3K6
Locus tag QEP54_RS02345 Protein ID WP_014829995.1
Coordinates 540561..541421 (+) Length 287 a.a.

Antitoxin (Protein)


Gene name abiEii Uniprot ID Q934C3
Locus tag QEP54_RS02340 Protein ID WP_013456322.1
Coordinates 539954..540568 (+) Length 205 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QEP54_RS02315 534955..535851 + 897 WP_099620149.1 variable surface lipoprotein -
QEP54_RS02320 536010..537116 + 1107 WP_280131282.1 variable surface lipoprotein -
QEP54_RS02325 537293..538072 + 780 WP_280131283.1 variable surface lipoprotein -
QEP54_RS02330 538248..538856 + 609 WP_115276525.1 variable surface lipoprotein -
QEP54_RS02335 539124..539771 - 648 WP_280131284.1 variable surface lipoprotein -
QEP54_RS02340 539954..540568 + 615 WP_013456322.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
QEP54_RS02345 540561..541421 + 861 WP_014829995.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
QEP54_RS02350 541542..542075 + 534 WP_280131285.1 variable surface lipoprotein -
QEP54_RS02355 542604..544037 + 1434 WP_101456648.1 transposase -
QEP54_RS02360 544040..544705 - 666 WP_235653895.1 variable surface lipoprotein -
QEP54_RS02365 544890..546275 - 1386 WP_101456733.1 variable surface lipoprotein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 532268..582982 50714


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(33-234)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(13-59)


Sequences

Toxin        


Download         Length: 287 a.a.        Molecular weight: 33280.36 Da        Isoelectric Point: 7.7731

>T278919 WP_014829995.1 NZ_CP123290:540561-541421 [Mycoplasmopsis bovis]
MNKNKLISLCHKTADQNNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNADDIDGIRYHILKYTDIRKEHKYSGINISVLCQIENIKQVISIDIASGDVITPKEIVYEYKSIFSNQD
FSILAYNIETMLSEKLETIFSFGHLNTRFKDFYDVYVIYTFKKKDIDINRLKDACYNTFKNRNSEFNIQQLLELITNIAF
NPLMNERKKYISQIANQQEIDFKAITNSIIELLELIKVNELTNND

Download         Length: 861 bp

Antitoxin


Download         Length: 205 a.a.        Molecular weight: 24143.83 Da        Isoelectric Point: 9.7617

>AT278919 WP_013456322.1 NZ_CP123290:539954-540568 [Mycoplasmopsis bovis]
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMITKGVLIRRAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE

Download         Length: 615 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2N8U3K6

Antitoxin

Source ID Structure
AlphaFold DB Q934C3

References