Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) abiEi-abiEii/AbiEii-AbiEi
Location 872792..874259 Replicon chromosome
Accession NZ_CP123289
Organism Mycoplasmopsis bovis strain 15DD0123

Toxin (Protein)


Gene name abiEi Uniprot ID Q932V7
Locus tag QEP62_RS03810 Protein ID WP_041309184.1
Coordinates 873399..874259 (+) Length 287 a.a.

Antitoxin (Protein)


Gene name abiEii Uniprot ID Q934C3
Locus tag QEP62_RS03805 Protein ID WP_013456322.1
Coordinates 872792..873406 (+) Length 205 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QEP62_RS03780 868282..868632 + 351 Protein_716 variable surface lipoprotein -
QEP62_RS03785 868900..869631 - 732 WP_075275861.1 variable surface lipoprotein -
QEP62_RS03790 869829..870455 - 627 WP_280124640.1 variable surface lipoprotein -
QEP62_RS03795 870641..871531 - 891 WP_075271150.1 variable surface lipoprotein -
QEP62_RS03800 871716..872609 - 894 WP_280135356.1 variable surface lipoprotein -
QEP62_RS03805 872792..873406 + 615 WP_013456322.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
QEP62_RS03810 873399..874259 + 861 WP_041309184.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
QEP62_RS03815 874379..874954 + 576 WP_075271397.1 variable surface lipoprotein -
QEP62_RS03820 874997..875722 - 726 WP_075271933.1 variable surface lipoprotein -
QEP62_RS03825 875937..876092 + 156 WP_180370284.1 hypothetical protein -
QEP62_RS03830 876305..876457 - 153 Protein_726 IS1634 family transposase -
QEP62_RS03835 876492..877736 - 1245 WP_013954691.1 IS3 family transposase -
QEP62_RS03840 877796..879061 - 1266 Protein_728 IS1634-like element ISMbov2 family transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 287 a.a.        Molecular weight: 33281.35 Da        Isoelectric Point: 7.2878

>T278918 WP_041309184.1 NZ_CP123289:873399-874259 [Mycoplasmopsis bovis]
MNKNKLISLCHKTADENNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNADDIDGIRYHILKYTDIRKEHKYSGINISVLCQIENIKQVISIDIASGDVITPKEIVYEYKSIFSNQD
FSILAYNIETMLSEKLETIFSFGHLNTRFKDFYDVYVIYTFKKKDIDINRLKDACYNTFKNRNSEFNIQQLLELITNIAF
NPLMNERKKYISQIANQQEIDFKAITNSIIELLELIKVNELTNND

Download         Length: 861 bp


Antitoxin


Download         Length: 205 a.a.        Molecular weight: 24143.83 Da        Isoelectric Point: 9.7617

>AT278918 WP_013456322.1 NZ_CP123289:872792-873406 [Mycoplasmopsis bovis]
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMITKGVLIRRAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE

Download         Length: 615 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB Q932V7


Antitoxin

Source ID Structure
AlphaFold DB Q934C3

References