Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | abiEi-abiEii/AbiEii-AbiEi |
Location | 279065..280532 | Replicon | chromosome |
Accession | NZ_CP123288 | ||
Organism | Mycoplasmopsis bovis strain 15DD0141 |
Toxin (Protein)
Gene name | abiEi | Uniprot ID | A0A2N8U3K6 |
Locus tag | QEP35_RS01300 | Protein ID | WP_014829995.1 |
Coordinates | 279065..279925 (-) | Length | 287 a.a. |
Antitoxin (Protein)
Gene name | abiEii | Uniprot ID | Q934C3 |
Locus tag | QEP35_RS01305 | Protein ID | WP_013456322.1 |
Coordinates | 279918..280532 (-) | Length | 205 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QEP35_RS01275 | 274496..274699 | - | 204 | WP_280135600.1 | variable surface lipoprotein | - |
QEP35_RS01280 | 275403..275624 | + | 222 | WP_280135601.1 | variable surface lipoprotein | - |
QEP35_RS01285 | 275621..276289 | - | 669 | WP_280135602.1 | hypothetical protein | - |
QEP35_RS01290 | 276320..277753 | - | 1434 | WP_101456648.1 | transposase | - |
QEP35_RS01295 | 278286..278945 | - | 660 | WP_280135611.1 | variable surface lipoprotein | - |
QEP35_RS01300 | 279065..279925 | - | 861 | WP_014829995.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
QEP35_RS01305 | 279918..280532 | - | 615 | WP_013456322.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
QEP35_RS01310 | 280715..281299 | + | 585 | WP_280135603.1 | variable surface lipoprotein | - |
QEP35_RS01315 | 281694..282011 | + | 318 | WP_280135619.1 | hypothetical protein | - |
QEP35_RS01320 | 282016..282123 | - | 108 | Protein_243 | variable surface lipoprotein | - |
QEP35_RS01325 | 282409..283158 | + | 750 | WP_013456123.1 | tyrosine-type recombinase/integrase | - |
QEP35_RS01335 | 283782..284810 | + | 1029 | WP_280135612.1 | IS30-like element ISMbov1 family transposase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | flank | IS/Tn | - | - | 283692..284810 | 1118 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 287 a.a. Molecular weight: 33280.36 Da Isoelectric Point: 7.7731
>T278917 WP_014829995.1 NZ_CP123288:c279925-279065 [Mycoplasmopsis bovis]
MNKNKLISLCHKTADQNNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNADDIDGIRYHILKYTDIRKEHKYSGINISVLCQIENIKQVISIDIASGDVITPKEIVYEYKSIFSNQD
FSILAYNIETMLSEKLETIFSFGHLNTRFKDFYDVYVIYTFKKKDIDINRLKDACYNTFKNRNSEFNIQQLLELITNIAF
NPLMNERKKYISQIANQQEIDFKAITNSIIELLELIKVNELTNND
MNKNKLISLCHKTADQNNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNADDIDGIRYHILKYTDIRKEHKYSGINISVLCQIENIKQVISIDIASGDVITPKEIVYEYKSIFSNQD
FSILAYNIETMLSEKLETIFSFGHLNTRFKDFYDVYVIYTFKKKDIDINRLKDACYNTFKNRNSEFNIQQLLELITNIAF
NPLMNERKKYISQIANQQEIDFKAITNSIIELLELIKVNELTNND
Download Length: 861 bp
Antitoxin
Download Length: 205 a.a. Molecular weight: 24143.83 Da Isoelectric Point: 9.7617
>AT278917 WP_013456322.1 NZ_CP123288:c280532-279918 [Mycoplasmopsis bovis]
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMITKGVLIRRAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMITKGVLIRRAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE
Download Length: 615 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2N8U3K6 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | Q934C3 |