278909

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 4010770..4011320 Replicon chromosome
Accession NZ_CP123282
Organism Salmonella sp. SA14318

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag QEN32_RS19125 Protein ID WP_265322031.1
Coordinates 4010770..4011078 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID V7ITQ8
Locus tag QEN32_RS19130 Protein ID WP_000016244.1
Coordinates 4011081..4011320 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QEN32_RS19110 (4008254) 4008254..4008370 + 117 Protein_3734 transposase -
QEN32_RS19115 (4008596) 4008596..4009612 - 1017 WP_265322030.1 IS110 family transposase -
QEN32_RS19120 (4009679) 4009679..4010646 + 968 Protein_3736 IS3 family transposase -
QEN32_RS19125 (4010770) 4010770..4011078 - 309 WP_265322031.1 CcdB family protein Toxin
QEN32_RS19130 (4011081) 4011081..4011320 - 240 WP_000016244.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
QEN32_RS19135 (4011433) 4011433..4011681 - 249 WP_050068098.1 ribbon-helix-helix domain-containing protein -
QEN32_RS19140 (4011758) 4011758..4012591 - 834 WP_197397882.1 DUF4942 domain-containing protein -
QEN32_RS19145 (4012745) 4012745..4013467 - 723 WP_080190675.1 retron system putative HNH endonuclease -
QEN32_RS19150 (4013464) 4013464..4013673 - 210 WP_139819174.1 hypothetical protein -
QEN32_RS19155 (4013670) 4013670..4014873 - 1204 Protein_3743 AAA family ATPase -
QEN32_RS19160 (4014967) 4014967..4015335 - 369 WP_076727515.1 TA system toxin CbtA family protein -
QEN32_RS19165 (4015350) 4015350..4015544 - 195 WP_265322078.1 type IV toxin-antitoxin system YeeU family antitoxin -
QEN32_RS19170 (4015489) 4015489..4015677 - 189 Protein_3746 DUF932 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-101)

Antitoxin

Post-segregation antitoxin CcdA

(9-79)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11827.63 Da        Isoelectric Point: 6.7228

>T278909 WP_265322031.1 NZ_CP123282:c4011078-4010770 [Salmonella sp. SA14318]
MQYMVYRNKGNSKAYPYLLDVQSDIIDELHTRIVIPLFPVSRLVNNPVKRLTPTLNVEGNDYLVMTHEMASIRLSQIGDE
VMDVRSHRQTIKNALDFIFDGF

Download         Length: 309 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8709.86 Da        Isoelectric Point: 6.4633

>AT278909 WP_000016244.1 NZ_CP123282:c4011320-4011081 [Salmonella sp. SA14318]
MSGMSVRHKKTVSVTLEPALLQQARDAGINLSAVLTAALKEEISATGVERWKAENRAGLQELNRITDEHGLLSDDYRTF

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A5I5T4R8

References