Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 854656..855316 Replicon chromosome
Accession NZ_CP123282
Organism Salmonella sp. SA14318

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag QEN32_RS04115 Protein ID WP_061377829.1
Coordinates 854903..855316 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag QEN32_RS04110 Protein ID WP_000351186.1
Coordinates 854656..854922 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QEN32_RS04090 (850584) 850584..852017 - 1434 WP_001230152.1 6-phospho-beta-glucosidase BglA -
QEN32_RS04095 (852176) 852176..852487 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
QEN32_RS04100 (852651) 852651..853310 + 660 WP_000250289.1 hemolysin III family protein -
QEN32_RS04105 (853426) 853426..854406 - 981 WP_000874176.1 tRNA-modifying protein YgfZ -
QEN32_RS04110 (854656) 854656..854922 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
QEN32_RS04115 (854903) 854903..855316 + 414 WP_061377829.1 protein YgfX Toxin
QEN32_RS04120 (855369) 855369..855890 - 522 WP_001055885.1 flavodoxin FldB -
QEN32_RS04125 (856003) 856003..856899 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
QEN32_RS04130 (856923) 856923..857636 + 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
QEN32_RS04135 (857642) 857642..859375 + 1734 WP_000813380.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16291.30 Da        Isoelectric Point: 11.1741

>T278899 WP_061377829.1 NZ_CP123282:854903-855316 [Salmonella sp. SA14318]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGH
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISRQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT278899 WP_000351186.1 NZ_CP123282:854656-854922 [Salmonella sp. SA14318]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References