Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4066323..4066983 Replicon chromosome
Accession NZ_CP123280
Organism Salmonella sp. SA17155

Toxin (Protein)


Gene name cptA Uniprot ID Q57K70
Locus tag QEN30_RS20225 Protein ID WP_000244756.1
Coordinates 4066570..4066983 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag QEN30_RS20220 Protein ID WP_000351186.1
Coordinates 4066323..4066589 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QEN30_RS20200 (4062251) 4062251..4063684 - 1434 WP_001230141.1 6-phospho-beta-glucosidase BglA -
QEN30_RS20205 (4063843) 4063843..4064154 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
QEN30_RS20210 (4064318) 4064318..4064977 + 660 WP_000250289.1 hemolysin III family protein -
QEN30_RS20215 (4065093) 4065093..4066073 - 981 WP_000874172.1 tRNA-modifying protein YgfZ -
QEN30_RS20220 (4066323) 4066323..4066589 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
QEN30_RS20225 (4066570) 4066570..4066983 + 414 WP_000244756.1 protein YgfX Toxin
QEN30_RS20230 (4067036) 4067036..4067557 - 522 WP_001055885.1 flavodoxin FldB -
QEN30_RS20235 (4067670) 4067670..4068566 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
QEN30_RS20240 (4068590) 4068590..4069303 + 714 WP_000745625.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
QEN30_RS20245 (4069309) 4069309..4071042 + 1734 WP_000813394.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16183.15 Da        Isoelectric Point: 10.7537

>T278893 WP_000244756.1 NZ_CP123280:4066570-4066983 [Salmonella sp. SA17155]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT278893 WP_000351186.1 NZ_CP123280:4066323-4066589 [Salmonella sp. SA17155]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E9V5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References