278881

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-YafN
Location 714297..714819 Replicon chromosome
Accession NZ_CP123280
Organism Salmonella sp. SA17155

Toxin (Protein)


Gene name stbE Uniprot ID B5F5Y5
Locus tag QEN30_RS03905 Protein ID WP_000221343.1
Coordinates 714535..714819 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID V1H457
Locus tag QEN30_RS03900 Protein ID WP_000885424.1
Coordinates 714297..714545 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QEN30_RS03875 (709513) 709513..710979 + 1467 WP_000987828.1 hypothetical protein -
QEN30_RS03880 (711787) 711787..712501 + 715 Protein_759 helix-turn-helix domain-containing protein -
QEN30_RS03885 (712557) 712557..713465 - 909 WP_010989018.1 hypothetical protein -
QEN30_RS03890 (713608) 713608..713940 - 333 WP_000253154.1 DUF1493 family protein -
QEN30_RS03895 (713930) 713930..714145 - 216 WP_000206207.1 hypothetical protein -
QEN30_RS03900 (714297) 714297..714545 + 249 WP_000885424.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QEN30_RS03905 (714535) 714535..714819 + 285 WP_000221343.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QEN30_RS03910 (714990) 714990..715379 + 390 WP_000194089.1 RidA family protein -
QEN30_RS03915 (715431) 715431..716510 - 1080 WP_000954688.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
QEN30_RS03920 (716703) 716703..717191 - 489 WP_280144419.1 MarR family winged helix-turn-helix transcriptional regulator -
QEN30_RS03925 (717236) 717236..718744 + 1509 WP_000199411.1 FAD-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 709516..721601 12085


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11075.85 Da        Isoelectric Point: 10.6500

>T278881 WP_000221343.1 NZ_CP123280:714535-714819 [Salmonella sp. SA17155]
MTYKLAFNESALKEWKKLGHTIQEQFKKKLRERLENPRVPASQLHGRKDQYKIKLRGAGYRLVYSVEDEIITVTVIGVGK
RENDAVYKMTRHRS

Download         Length: 285 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9090.32 Da        Isoelectric Point: 3.9820

>AT278881 WP_000885424.1 NZ_CP123280:714297-714545 [Salmonella sp. SA17155]
MAFQILTTTAASITELKRDPMGTFNAGDGAPVAILNRNEPAFYCVPPALYAHLMDILEDEELGRIIDERANERVIEVNID
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5H5JSW4

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0WPN5

References