Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2100089..2100360 Replicon chromosome
Accession NZ_CP123266
Organism Escherichia coli strain YZLc23-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2100219..2100322 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2100089..2100360 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N4686_RS10145 2096644..2097306 - 663 WP_000944256.1 exodeoxyribonuclease X -
N4686_RS10150 2097330..2097986 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
N4686_RS10155 2098088..2098318 - 231 WP_000916763.1 DNA polymerase III subunit theta -
N4686_RS10160 2098457..2098831 + 375 WP_000204699.1 CopC domain-containing protein YobA -
N4686_RS10165 2098835..2099707 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
N4686_RS10170 2099720..2100061 + 342 WP_000976492.1 YebY family protein -
- 2100089..2100360 - 272 - - Antitoxin
- 2100219..2100322 + 104 - - Toxin
N4686_RS10175 2100457..2101113 + 657 WP_024258105.1 protein-serine/threonine phosphatase -
N4686_RS10180 2101114..2101305 - 192 WP_001296140.1 YebW family protein -
N4686_RS10185 2101410..2101646 - 237 WP_001295499.1 YebV family protein -
N4686_RS10190 2101764..2103203 - 1440 WP_001512833.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T278853 NZ_CP123266:2100219-2100322 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT278853 NZ_CP123266:c2100360-2100089 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGTAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References