Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relB-yefM/YoeB-RelB |
| Location | 104162..104672 | Replicon | plasmid pYZLc5-3_NDM-1_129k |
| Accession | NZ_CP123252 | ||
| Organism | Providencia rettgeri strain YZLc5-3 | ||
Toxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | N4838_RS21390 | Protein ID | WP_019281448.1 |
| Coordinates | 104162..104425 (-) | Length | 88 a.a. |
Antitoxin (Protein)
| Gene name | yefM | Uniprot ID | A0A7X5B7D9 |
| Locus tag | N4838_RS21395 | Protein ID | WP_009836585.1 |
| Coordinates | 104418..104672 (-) | Length | 85 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| N4838_RS21360 (N4838_021435) | 99183..99932 | + | 750 | WP_071547986.1 | signal peptidase I | - |
| N4838_RS21365 (N4838_021440) | 100012..100269 | + | 258 | WP_206091104.1 | hypothetical protein | - |
| N4838_RS21375 (N4838_021455) | 101825..102235 | - | 411 | WP_206086781.1 | IS200/IS605 family transposase | - |
| N4838_RS21380 (N4838_021460) | 102290..103495 | + | 1206 | WP_284183216.1 | transposase | - |
| N4838_RS21385 (N4838_021465) | 103539..103883 | + | 345 | Protein_115 | transposase | - |
| N4838_RS21390 (N4838_021470) | 104162..104425 | - | 264 | WP_019281448.1 | Txe/YoeB family addiction module toxin | Toxin |
| N4838_RS21395 (N4838_021475) | 104418..104672 | - | 255 | WP_009836585.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
| N4838_RS21400 (N4838_021480) | 105033..106007 | + | 975 | WP_223674028.1 | IS5-like element IS5 family transposase | - |
| N4838_RS21405 (N4838_021485) | 106152..106319 | - | 168 | Protein_119 | glycerol dehydratase reactivase beta/small subunit family protein | - |
| N4838_RS21410 (N4838_021490) | 106336..107499 | - | 1164 | WP_016243884.1 | 1,3-propanediol dehydrogenase | - |
| N4838_RS21415 (N4838_021495) | 107644..107936 | - | 293 | Protein_121 | hypothetical protein | - |
| N4838_RS21420 (N4838_021500) | 108033..108353 | + | 321 | WP_206086774.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| N4838_RS21425 (N4838_021505) | 108563..108724 | - | 162 | Protein_123 | transposase | - |
| N4838_RS21430 (N4838_021510) | 108753..109085 | - | 333 | WP_125894547.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | dfrA12 / aadA2 / aph(3')-Ia / aac(3)-IVa / aph(4)-Ia / sul2 / floR / aac(6')-Ib-cr / ARR-3 / qacE / sul1 / blaNDM-1 / mph(E) / msr(E) / tet(B) | - | 1..129473 | 129473 | |
| - | inside | IScluster/Tn | - | - | 100971..108622 | 7651 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|