Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4264949..4265492 Replicon chromosome
Accession NZ_CP123251
Organism Providencia rettgeri strain YZLc5-3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N4838_RS19480 Protein ID WP_262961201.1
Coordinates 4264949..4265248 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N4838_RS19485 Protein ID WP_196725047.1
Coordinates 4265238..4265492 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N4838_RS19450 (N4838_019515) 4260496..4261782 - 1287 WP_112308117.1 N-acetylmuramoyl-L-alanine amidase AmiB -
N4838_RS19455 (N4838_019520) 4261797..4262261 - 465 WP_004906013.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
N4838_RS19460 (N4838_019525) 4262550..4263731 + 1182 WP_136134035.1 tRNA epoxyqueuosine(34) reductase QueG -
N4838_RS19480 (N4838_019545) 4264949..4265248 - 300 WP_262961201.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N4838_RS19485 (N4838_019550) 4265238..4265492 - 255 WP_196725047.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
N4838_RS19490 (N4838_019555) 4265677..4266222 - 546 WP_196725048.1 oligoribonuclease -
N4838_RS19495 (N4838_019560) 4266334..4267386 + 1053 WP_004906021.1 small ribosomal subunit biogenesis GTPase RsgA -
N4838_RS19500 (N4838_019565) 4267543..4268439 + 897 WP_136134032.1 archaetidylserine decarboxylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-74)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11862.04 Da        Isoelectric Point: 10.2463

>T278790 WP_262961201.1 NZ_CP123251:c4265248-4264949 [Providencia rettgeri]
MIFDIVFDERALREWKKLDYSIREQFKKKLKKLKKLQLNPYIESLRLHGELSNCYKIKLRASGFRLVYQVVDDEIVIFVV
AVGKREDKKVYNSAIERLP

Download         Length: 300 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9777.17 Da        Isoelectric Point: 4.6838

>AT278790 WP_196725047.1 NZ_CP123251:c4265492-4265238 [Providencia rettgeri]
MSTIQIRVDEQLKRDAYQAFDKLNLSPSDALRLFLRYVAENEKLPFSEVSIVVSETDEDEDILAVVRERLKKPAKRIRVN
IDDI

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References