Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-HTH_XRE
Location 4194868..4195576 Replicon chromosome
Accession NZ_CP123251
Organism Providencia rettgeri strain YZLc5-3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N4838_RS19125 Protein ID WP_262960865.1
Coordinates 4195208..4195576 (-) Length 123 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N4838_RS19120 Protein ID WP_004905885.1
Coordinates 4194868..4195197 (-) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N4838_RS19105 (N4838_019175) 4190938..4191909 - 972 WP_004905881.1 efflux RND transporter periplasmic adaptor subunit -
N4838_RS19110 (N4838_019180) 4192442..4194127 + 1686 WP_094961673.1 sensor histidine kinase -
N4838_RS19115 (N4838_019185) 4194147..4194863 + 717 WP_004905884.1 two-component system response regulator BtsR -
N4838_RS19120 (N4838_019190) 4194868..4195197 - 330 WP_004905885.1 helix-turn-helix domain-containing protein Antitoxin
N4838_RS19125 (N4838_019195) 4195208..4195576 - 369 WP_262960865.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N4838_RS19130 (N4838_019200) 4195730..4197661 - 1932 WP_110591058.1 DEAD/DEAH family ATP-dependent RNA helicase -
N4838_RS19135 (N4838_019205) 4197832..4198749 - 918 WP_262960864.1 lipoprotein NlpI -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(4-120)

Antitoxin

Cro/C1-type helix-turn-helix domain

(53-93)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13714.02 Da        Isoelectric Point: 9.9893

>T278789 WP_262960865.1 NZ_CP123251:c4195576-4195208 [Providencia rettgeri]
VAFYKISSFKRSTKKIKIMDKHLLKATNEVLAGVYEADLGSGVIKKRIAINGKGKSGGVRVIIFFKVSHHLFFADGWEKC
NIAAKGVKEIEDDELDAYKNLSRLFLNYTDDKIADLVLHNIL

Download         Length: 369 bp

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12235.50 Da        Isoelectric Point: 10.3803

>AT278789 WP_004905885.1 NZ_CP123251:c4195197-4194868 [Providencia rettgeri]
MSNKLENMLELAKELHQVDAAPKSLVTDLEQKVGNRKINNKIKVVPMMSGAQIKQLRAQYGMSQAMLALALGMSKESVSK
WEREEKKPSGPALRMLHLIEQRGPEILII

Download         Length: 330 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References