Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1532202..1532859 Replicon chromosome
Accession NZ_CP123251
Organism Providencia rettgeri strain YZLc5-3

Toxin (Protein)


Gene name cptA Uniprot ID A0A264VM08
Locus tag N4838_RS06635 Protein ID WP_036958456.1
Coordinates 1532449..1532859 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID D4C097
Locus tag N4838_RS06630 Protein ID WP_004261864.1
Coordinates 1532202..1532468 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N4838_RS06615 (N4838_006625) 1529198..1530094 - 897 WP_167732490.1 hypothetical protein -
N4838_RS06620 (N4838_006630) 1530339..1530959 - 621 WP_004261871.1 HD domain-containing protein -
N4838_RS06625 (N4838_006635) 1530971..1531954 - 984 WP_112307213.1 tRNA-modifying protein YgfZ -
N4838_RS06630 (N4838_006640) 1532202..1532468 + 267 WP_004261864.1 FAD assembly factor SdhE Antitoxin
N4838_RS06635 (N4838_006645) 1532449..1532859 + 411 WP_036958456.1 protein YgfX Toxin
N4838_RS06640 (N4838_006650) 1532959..1533477 - 519 WP_094963000.1 flavodoxin FldB -
N4838_RS06645 (N4838_006655) 1533595..1534497 + 903 WP_004261814.1 site-specific tyrosine recombinase XerD -
N4838_RS06650 (N4838_006660) 1534519..1535223 + 705 WP_096863312.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
N4838_RS06655 (N4838_006665) 1535233..1536966 + 1734 WP_110592137.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15568.53 Da        Isoelectric Point: 10.7733

>T278785 WP_036958456.1 NZ_CP123251:1532449-1532859 [Providencia rettgeri]
VVLWKSNLSISWKTQLFSTCVHGVIGMFLLLAPWSPGNSMIWLPLLVVVVASWAKSQKNISKIKGVAVLVNGNKVQWKKN
EWRILKAPWLTRYGILLTLEALQGKPQKLHLWVAKDALSEENWRNLNQLLLQYPDI

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10684.24 Da        Isoelectric Point: 4.8942

>AT278785 WP_004261864.1 NZ_CP123251:1532202-1532468 [Providencia rettgeri]
MDIENKARIHWACRRGMRELDISIMPFFEYEYDDLTTHDKQVFVRLLECADPDLFNWLMNHGRPDDDELFRMIKLIQEKN
KNRGPVEI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A264VM08

Antitoxin

Source ID Structure
AlphaFold DB A0A345M2Q5

References