Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelE(toxin)
Location 121620..122192 Replicon plasmid pTM1
Accession NC_017957
Organism Tistrella mobilis KA081020-065

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag TMO_RS30590 Protein ID WP_081599039.1
Coordinates 121620..121898 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag TMO_RS18500 Protein ID WP_041606870.1
Coordinates 121902..122192 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TMO_RS18475 116767..117759 - 993 WP_014747188.1 alpha/beta hydrolase -
TMO_RS18480 117861..118490 + 630 WP_014747189.1 FMN-binding negative transcriptional regulator -
TMO_RS18485 118522..119283 - 762 WP_041606997.1 metallophosphoesterase -
TMO_RS18490 119527..120717 + 1191 WP_014747191.1 MFS transporter -
TMO_RS18495 120779..121609 + 831 WP_014747192.1 AraC family transcriptional regulator -
TMO_RS30590 121620..121898 - 279 WP_081599039.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
TMO_RS18500 121902..122192 - 291 WP_041606870.1 hypothetical protein Antitoxin
TMO_RS18505 122486..122764 + 279 WP_145978283.1 CopG family transcriptional regulator -
TMO_RS18510 122765..123076 + 312 WP_014747196.1 type II toxin-antitoxin system RelE/ParE family toxin -
TMO_RS18515 123161..124144 + 984 WP_014747197.1 DMT family transporter -
TMO_RS18520 124108..125820 - 1713 WP_014747198.1 ABC transporter ATP-binding protein/permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..692456 692456


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(1-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10607.42 Da        Isoelectric Point: 11.5429

>T27877 WP_081599039.1 NC_017957:c121898-121620 [Tistrella mobilis KA081020-065]
IVWTPQALRSRQEIRRYIAADDLAAALVLDELFRAKALQLVLYPSLGRPGRVHGTRELMVHRNYILVYQLSVDSVRILHV
LHAARRWPPGSR

Download         Length: 279 bp

>T27877 NC_017957:c121898-121620 [Tistrella mobilis KA081020-065]
ATTGTCTGGACGCCCCAGGCACTCAGAAGCCGACAGGAAATTCGTCGCTACATTGCTGCTGATGATTTGGCAGCTGCACT
TGTGCTGGACGAGCTTTTCCGAGCAAAGGCGCTCCAGTTGGTGCTCTATCCATCTCTGGGACGGCCTGGTCGTGTCCATG
GCACACGCGAGCTGATGGTCCATCGCAACTACATCCTGGTCTATCAGCTGAGCGTTGATTCGGTTCGGATATTGCACGTG
CTGCATGCCGCGCGCCGCTGGCCTCCTGGGTCGCGCTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10734.72 Da        Isoelectric Point: 4.1790

>AT27877 WP_041606870.1 NC_017957:c122192-121902 [Tistrella mobilis KA081020-065]
MAETTFTFQVDEGLKDAFAEAAKGSDRTGAELLRDFMRDYVRDQVEAAAYDRWFRREVEAAIAEADAGNVVSSDDVEADA
EIWRAEIRRRLNGAAS

Download         Length: 291 bp

>AT27877 NC_017957:c122192-121902 [Tistrella mobilis KA081020-065]
ATGGCCGAGACCACCTTTACCTTTCAGGTCGATGAAGGACTGAAGGATGCGTTTGCCGAAGCGGCGAAGGGCAGTGATCG
TACCGGCGCCGAACTTCTGCGTGACTTCATGCGGGACTATGTTCGAGACCAGGTCGAGGCTGCAGCCTATGACCGGTGGT
TTCGGCGTGAAGTGGAGGCGGCCATCGCCGAGGCTGATGCGGGCAATGTCGTATCCAGTGATGATGTTGAAGCTGATGCC
GAGATTTGGCGGGCAGAAATCCGGCGCAGGTTGAACGGCGCCGCTTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References