Detailed information of TA system TA027874

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ataRT/DUF1778(antitoxin)
• Location: 3034455..3035314
• Replicon: chromosome
• Accession: NC_017956
• Organism: Tistrella mobilis KA081020-065

Toxin (Protein)

• Gene name: ataT
• Uniprot ID: -
• Locus tag: TMO_RS13820
• Protein ID: WP_041604972.1
• Coordinates: 3034455..3034982 (-)
• Length: 176 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: -
• Locus tag: TMO_RS13825
• Protein ID: WP_041604974.1
• Coordinates: 3034970..3035314 (-)
• Length: 115 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
TMO_RS13800	3029862..3030698	+	837	WP_014746252.1	metal ABC transporter permease	-
TMO_RS13805	3030785..3031390	+	606	WP_014746253.1	response regulator transcription factor	-
TMO_RS13810	3031405..3033165	+	1761	WP_145978136.1	sensor histidine kinase	-
TMO_RS13815	3033293..3034462	+	1170	WP_145978137.1	hypothetical protein	-
TMO_RS13820	3034455..3034982	-	528	WP_041604972.1	GNAT family N-acetyltransferase	Toxin
TMO_RS13825	3034970..3035314	-	345	WP_041604974.1	DUF1778 domain-containing protein	Antitoxin
TMO_RS13830	3035458..3037044	-	1587	WP_041606371.1	lysine--tRNA ligase	-
TMO_RS13835	3037259..3040222	+	2964	WP_014746259.1	ATP-dependent DNA helicase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (50-148)

Antitoxin

• Vibrio phage ICP1, Orf50 (33-108)

Sequences

Toxin

Protein

• Length: 176 a.a.
• Molecular weight: 18901.71 Da
• Isoelectric Point: 7.1901

>T27874 WP_041604972.1 NC_017956:c3034982-3034455 [Tistrella mobilis KA081020-065]
MGEIGGEIEGGEALTSPQPLSPEHDLSTFSCGTPELDAWLRHRALRNEGRFSRTYVMCRGRKVVGYYCISAGALGRAAVP
GKLRRNAPDMIPVSVIGRLAVSLDHAGQGLGADLLLDAFGRIAAASRTLGISAVLVQAKDERARRFYLNCADFIEYPEES
RLLLLPIETVIAAFS

Nucleotide

• Length: 528 bp

>T27874 NC_017956:c3034982-3034455 [Tistrella mobilis KA081020-065]
ATGGGAGAAATAGGCGGCGAGATCGAGGGTGGAGAGGCGCTGACCTCTCCCCAGCCCCTCAGCCCTGAGCATGATTTATC
AACTTTTAGTTGCGGGACGCCTGAGCTGGATGCCTGGCTGCGGCATCGTGCCCTCCGCAACGAAGGCCGTTTCTCAAGAA
CCTATGTGATGTGCCGCGGCCGGAAGGTGGTTGGCTATTACTGCATTTCAGCGGGGGCTCTCGGGCGTGCTGCCGTTCCC
GGCAAGCTGCGTCGGAATGCCCCCGACATGATACCTGTGTCGGTCATCGGCCGTCTGGCGGTCAGCCTGGATCACGCCGG
GCAGGGCCTCGGCGCCGATCTGTTGTTGGACGCGTTTGGTCGTATCGCCGCCGCATCTCGCACCCTTGGCATAAGTGCCG
TGCTCGTACAGGCGAAGGACGAACGCGCCAGGCGCTTCTACCTGAACTGCGCTGATTTCATCGAGTACCCGGAAGAAAGC
CGCCTGCTCCTGCTTCCGATCGAGACGGTCATCGCGGCCTTCAGCTGA

Antitoxin

Protein

• Length: 115 a.a.
• Molecular weight: 12621.58 Da
• Isoelectric Point: 10.2596

>AT27874 WP_041604974.1 NC_017956:c3035314-3034970 [Tistrella mobilis KA081020-065]
MTRIRRPAMHDAPDAFATTVAERGAAPDAKASINLRIDAGTRQLIDEAAQALGKTRTEFMVESARSLAIDVILDQRLFLL
DPARYDAFLQVLDNPPAPGPKLRKLVKRTPAWEK

Nucleotide

• Length: 345 bp

>AT27874 NC_017956:c3035314-3034970 [Tistrella mobilis KA081020-065]
ATGACCAGGATCCGCAGACCCGCCATGCATGATGCTCCGGATGCCTTCGCGACCACAGTTGCGGAGCGTGGCGCTGCGCC
GGATGCCAAGGCCAGCATCAATCTCAGGATTGATGCCGGAACCCGGCAGCTTATCGACGAGGCAGCGCAGGCACTGGGCA
AGACCCGCACCGAGTTCATGGTCGAAAGTGCCCGCAGTCTCGCCATTGACGTGATCCTCGACCAGCGGCTCTTTCTGCTC
GATCCGGCGCGTTACGACGCCTTTCTGCAGGTGCTCGACAATCCCCCCGCGCCCGGACCGAAGCTCCGCAAACTCGTCAA
GCGGACACCGGCATGGGAGAAATAG