Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2291935..2292206 Replicon chromosome
Accession NZ_CP123240
Organism Escherichia coli strain YZLc1-3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2292065..2292168 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2291935..2292206 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N4725_RS11195 2288490..2289152 - 663 WP_000944256.1 exodeoxyribonuclease X -
N4725_RS11200 2289176..2289832 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
N4725_RS11205 2289934..2290164 - 231 WP_000916763.1 DNA polymerase III subunit theta -
N4725_RS11210 2290303..2290677 + 375 WP_000168747.1 CopC domain-containing protein YobA -
N4725_RS11215 2290681..2291553 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
N4725_RS11220 2291566..2291907 + 342 WP_000976472.1 YebY family protein -
- 2291935..2292206 - 272 - - Antitoxin
- 2292065..2292168 + 104 - - Toxin
N4725_RS11225 2292303..2292959 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
N4725_RS11230 2292960..2293151 - 192 WP_001296140.1 YebW family protein -
N4725_RS11235 2293256..2293492 - 237 WP_001295499.1 YebV family protein -
N4725_RS11240 2293610..2295049 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2284625..2308046 23421
- inside Prophage - - 2282762..2308046 25284


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T278733 NZ_CP123240:2292065-2292168 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT278733 NZ_CP123240:c2292206-2291935 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References