Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 1078299..1078816 Replicon chromosome
Accession NC_017956
Organism Tistrella mobilis KA081020-065

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag TMO_RS30270 Protein ID WP_081598774.1
Coordinates 1078601..1078816 (-) Length 72 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag TMO_RS30265 Protein ID WP_014744498.1
Coordinates 1078299..1078598 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TMO_RS04900 1074051..1075232 + 1182 WP_014744493.1 lipid-transfer protein -
TMO_RS04905 1075263..1075730 + 468 WP_014744494.1 MaoC family dehydratase N-terminal domain-containing protein -
TMO_RS04910 1075727..1076113 + 387 WP_014744495.1 MaoC family dehydratase -
TMO_RS04915 1076176..1077003 + 828 WP_014744496.1 SDR family oxidoreductase -
TMO_RS04920 1077116..1078240 + 1125 WP_145978198.1 acyl-CoA dehydrogenase family protein -
TMO_RS30265 1078299..1078598 - 300 WP_014744498.1 putative addiction module antidote protein Antitoxin
TMO_RS30270 1078601..1078816 - 216 WP_081598774.1 hypothetical protein Toxin
TMO_RS04925 1078869..1079828 - 960 WP_014744499.1 PhzF family phenazine biosynthesis protein -
TMO_RS04930 1079934..1080524 - 591 WP_014744500.1 peroxidase-related enzyme -
TMO_RS04935 1080603..1081676 - 1074 WP_014744501.1 chorismate synthase -
TMO_RS04940 1081723..1082535 - 813 WP_014744502.1 enoyl-ACP reductase FabI -
TMO_RS04945 1082737..1083690 - 954 WP_014744503.1 YihY/virulence factor BrkB family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(16-68)

Antitoxin

Cro/C1-type helix-turn-helix domain

(47-89)


Sequences

Toxin        


Download         Length: 72 a.a.        Molecular weight: 8039.25 Da        Isoelectric Point: 9.1635

>T27872 WP_081598774.1 NC_017956:c1078816-1078601 [Tistrella mobilis KA081020-065]
ILQIKSSKNYCLPHALVRQGVSELRIHEGPGYRVYFAQRGTVLIVLLCGGTNNRQNDDIEQAKRLAAEMER

Download         Length: 216 bp

>T27872 NC_017956:c1078816-1078601 [Tistrella mobilis KA081020-065]
ATTCTCCAGATAAAATCATCTAAAAACTACTGTCTGCCGCATGCGCTGGTGCGGCAGGGTGTTTCCGAGCTGCGCATTCA
TGAGGGACCAGGGTATAGGGTTTACTTCGCCCAGCGTGGCACTGTTCTTATTGTTCTTCTATGCGGTGGCACGAATAACC
GTCAAAATGACGACATTGAGCAAGCAAAGAGACTTGCGGCGGAAATGGAGAGGTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10528.82 Da        Isoelectric Point: 4.0262

>AT27872 WP_014744498.1 NC_017956:c1078598-1078299 [Tistrella mobilis KA081020-065]
MALETTAFDPAEYLDDDEAMAGYLSDAFETGDPAFISDALGVVARAKGMRQIAEDAGLSRESLYRALSDKGNPEFGTILK
VLAALGLRLSVEPLPHPGE

Download         Length: 300 bp

>AT27872 NC_017956:c1078598-1078299 [Tistrella mobilis KA081020-065]
ATGGCGCTGGAGACCACGGCCTTTGATCCGGCAGAATATCTGGACGATGACGAGGCTATGGCCGGCTATCTATCCGATGC
GTTCGAAACAGGAGACCCTGCGTTTATTTCCGACGCGTTGGGCGTCGTGGCACGCGCTAAAGGAATGAGACAGATTGCCG
AAGATGCAGGACTCTCCCGCGAAAGCCTCTATCGAGCCTTGAGCGACAAGGGAAATCCCGAATTCGGAACTATACTGAAA
GTTCTGGCTGCCCTTGGTCTTCGTCTTTCTGTAGAACCGCTGCCTCACCCCGGGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References