Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yjhX-yjhQ/YjhX-GNAT |
Location | 4163567..4164381 | Replicon | chromosome |
Accession | NZ_CP123231 | ||
Organism | Escherichia coli strain 5132 |
Toxin (Protein)
Gene name | yjhX | Uniprot ID | S1PA82 |
Locus tag | QET41_RS20300 | Protein ID | WP_001054376.1 |
Coordinates | 4163567..4163824 (+) | Length | 86 a.a. |
Antitoxin (Protein)
Gene name | yjhQ | Uniprot ID | S1NWL7 |
Locus tag | QET41_RS20305 | Protein ID | WP_001540600.1 |
Coordinates | 4163836..4164381 (+) | Length | 182 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QET41_RS20275 (4158855) | 4158855..4159961 | + | 1107 | WP_001774143.1 | N-acetylneuraminate epimerase | - |
QET41_RS20280 (4160026) | 4160026..4161006 | + | 981 | WP_000991438.1 | 9-O-acetyl-N-acetylneuraminic acid deacetylase | - |
QET41_RS20285 (4161116) | 4161116..4161321 | + | 206 | Protein_3971 | HNH endonuclease | - |
QET41_RS20290 (4161589) | 4161589..4162829 | - | 1241 | Protein_3972 | helicase YjhR | - |
QET41_RS20295 (4162945) | 4162945..4163076 | + | 132 | WP_001309182.1 | hypothetical protein | - |
QET41_RS20300 (4163567) | 4163567..4163824 | + | 258 | WP_001054376.1 | YjhX family toxin | Toxin |
QET41_RS20305 (4163836) | 4163836..4164381 | + | 546 | WP_001540600.1 | N-acetyltransferase | Antitoxin |
QET41_RS20310 (4164437) | 4164437..4165183 | + | 747 | WP_000354251.1 | class I SAM-dependent methyltransferase | - |
QET41_RS20315 (4165352) | 4165352..4165570 | + | 219 | Protein_3977 | hypothetical protein | - |
QET41_RS20320 (4165608) | 4165608..4165724 | + | 117 | Protein_3978 | VOC family protein | - |
QET41_RS20325 (4165969) | 4165969..4167090 | + | 1122 | WP_000010829.1 | M42 family metallopeptidase | - |
QET41_RS20330 (4167087) | 4167087..4167365 | + | 279 | WP_000722973.1 | PTS sugar transporter subunit IIB SgcB | - |
QET41_RS20335 (4167377) | 4167377..4168690 | + | 1314 | WP_000460843.1 | PTS sugar transporter subunit IIC SgcC | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | fimI / fimA / fimE / fimB | 4153353..4172605 | 19252 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 9734.29 Da Isoelectric Point: 11.0090
>T278690 WP_001054376.1 NZ_CP123231:4163567-4163824 [Escherichia coli]
MNLSRQEQHTLHVLAKGRRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTELNKVRA
QLDNR
MNLSRQEQHTLHVLAKGRRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTELNKVRA
QLDNR
Download Length: 258 bp
Antitoxin
Download Length: 182 a.a. Molecular weight: 19926.87 Da Isoelectric Point: 6.3277
>AT278690 WP_001540600.1 NZ_CP123231:4163836-4164381 [Escherichia coli]
MTVHHFTFHITDKSDASDIREVETRAFGFGKEADLVASLLEDESARPALSLLARYEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQSLTA
QPMTLTGHIRCADPDETGALT
MTVHHFTFHITDKSDASDIREVETRAFGFGKEADLVASLLEDESARPALSLLARYEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQSLTA
QPMTLTGHIRCADPDETGALT
Download Length: 546 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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