Detailed information of TA system TA278668

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 1627609..1629116
• Replicon: chromosome
• Accession: NZ_CP123228
• Organism: Piscinibacter sp. XHJ-5

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: P7V53_RS07645
• Protein ID: WP_280154889.1
• Coordinates: 1627609..1628487 (-)
• Length: 293 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: P7V53_RS07650
• Protein ID: WP_280154890.1
• Coordinates: 1628511..1629116 (-)
• Length: 202 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
P7V53_RS07620	1623016..1624167	+	1152	WP_280154884.1	extracellular solute-binding protein	-
P7V53_RS07625	1624217..1625041	+	825	WP_280154885.1	ABC transporter permease subunit	-
P7V53_RS07630	1625038..1625862	+	825	WP_280154886.1	ABC transporter permease subunit	-
P7V53_RS07635	1625864..1626715	+	852	WP_280154887.1	inositol monophosphatase	-
P7V53_RS07640	1626725..1627255	+	531	WP_280154888.1	hypothetical protein	-
P7V53_RS07645	1627609..1628487	-	879	WP_280154889.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
P7V53_RS07650	1628511..1629116	-	606	WP_280154890.1	AbiEi antitoxin N-terminal domain-containing protein	Antitoxin
P7V53_RS07655	1629232..1629785	+	554	Protein_1507	DUF932 domain-containing protein	-
P7V53_RS07660	1629868..1631030	-	1163	Protein_1508	IS3 family transposase	-
P7V53_RS07665	1631244..1631915	-	672	WP_280154891.1	acyltransferase	-
P7V53_RS07670	1631928..1632077	-	150	WP_280154892.1	hypothetical protein	-
P7V53_RS07675	1632649..1633713	-	1065	WP_280154893.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (27-253)

Antitoxin

• Transcriptional regulator AbiEi antitoxin, N-terminal domain (13-83)

Sequences

Toxin

Protein

• Length: 293 a.a.
• Molecular weight: 32509.10 Da
• Isoelectric Point: 5.7554

>T278668 WP_280154889.1 NZ_CP123228:c1628487-1627609 [Piscinibacter sp. XHJ-5]
VLARLLDLAKQGGQDYSLLLNRFGLERLLDRLTKSRHADRFLLKGALLFSLWYDEPHRPTRDADLLGFGPDDAEHLATVF
REIAAIELDDGIVFDPDSVRVDPIREDNAYGGSRIRLVGHVGNARCSLQVDVGFGDAVTPSPETARYPVLLPDFDRPTLR
VYPVYTVIAEKYQAMVTLGAANSRVKDFYDLCMIASRTSLDGQTLARAITATFTRRITEIPAEPPLALRPAFSNDSAKQQ
QWRAFLSRNRLGEIELAVAIELLYALLWPPTQVAGSASDATARWDAALLKWV

Nucleotide

• Length: 879 bp

Antitoxin

Protein

• Length: 202 a.a.
• Molecular weight: 22604.33 Da
• Isoelectric Point: 9.8115

>AT278668 WP_280154890.1 NZ_CP123228:c1629116-1628511 [Piscinibacter sp. XHJ-5]
MTGSSMERVMALAADRRLLRGSDLHDVGLSPQLLIKLHQAGKLQRVFRGVYSLPDAPVTEHQSLAEVCRRVPKGVVCLLS
ALRFHEIGTQAPHEVWLALPESSRTPAVSFPALRIVRLRGEAYSESIETVMEEGASIRVYSTAKTITDCFKFRHKIGLDV
ALEALKDAWQRRLVKMDDLSRFARINRVERVMQPYLEALVA

Nucleotide

• Length: 606 bp