Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/-
Location 1329..1807 Replicon plasmid pPae2250I
Accession NZ_CP123224
Organism Pseudomonas amygdali pv. aesculi strain 2250

Toxin (Protein)


Gene name relE Uniprot ID A0A2S4ICR4
Locus tag QEP70_RS28475 Protein ID WP_005730619.1
Coordinates 1329..1622 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2S4HLF9
Locus tag QEP70_RS28480 Protein ID WP_003348562.1
Coordinates 1622..1807 (-) Length 62 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QEP70_RS28465 1..666 + 666 WP_010206144.1 MobA/MobL family protein -
QEP70_RS28470 728..1189 - 462 WP_005734737.1 hypothetical protein -
QEP70_RS28475 1329..1622 - 294 WP_005730619.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QEP70_RS28480 1622..1807 - 186 WP_003348562.1 hypothetical protein Antitoxin
QEP70_RS28490 3314..3586 - 273 WP_060406870.1 hypothetical protein -
QEP70_RS28495 3680..4315 - 636 WP_060406871.1 recombinase family protein -
QEP70_RS28500 4816..5466 + 651 WP_003344252.1 ParA family protein -
QEP70_RS28505 5547..5837 + 291 WP_010217231.1 hypothetical protein -
QEP70_RS28510 5911..6054 + 144 WP_155511877.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..65883 65883


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11192.94 Da        Isoelectric Point: 6.2150

>T278663 WP_005730619.1 NZ_CP123224:c1622-1329 [Pseudomonas amygdali pv. aesculi]
MLPIFWLESADNDLAAIIEYIGLRDIAAAERLWQRLRSIVLPLSEHPYLYAISDRVPGMREIVAHPNYLVFYRVTSTRIE
VVNVVHARQEYPQTGLA

Download         Length: 294 bp

Antitoxin


Download         Length: 62 a.a.        Molecular weight: 7134.04 Da        Isoelectric Point: 6.4675

>AT278663 WP_003348562.1 NZ_CP123224:c1807-1622 [Pseudomonas amygdali pv. aesculi]
MIDRSPIVSEFETEELEANYTAWLRAKVEASLADSRPAIPHDEVERRMAERLARLRHRRAS

Download         Length: 186 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2S4ICR4

Antitoxin

Source ID Structure
AlphaFold DB A0A2S4HLF9

References