Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 84788..85235 Replicon plasmid pCOR2203
Accession NZ_CP123216
Organism Pseudomonas amygdali pv. aesculi strain 2203

Toxin (Protein)


Gene name relE Uniprot ID E7PTW5
Locus tag QEP68_RS28280 Protein ID WP_004662083.1
Coordinates 84788..85060 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID E7PTW6
Locus tag QEP68_RS28285 Protein ID WP_003381808.1
Coordinates 85050..85235 (-) Length 62 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QEP68_RS28260 81620..81769 - 150 Protein_96 ATP-binding protein -
QEP68_RS28270 83498..83725 - 228 WP_057413040.1 hypothetical protein -
QEP68_RS28275 83971..84684 - 714 WP_060409922.1 YecA family protein -
QEP68_RS28280 84788..85060 - 273 WP_004662083.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QEP68_RS28285 85050..85235 - 186 WP_003381808.1 hypothetical protein Antitoxin
QEP68_RS28290 85482..86711 - 1230 WP_280124528.1 IS91 family transposase -
QEP68_RS28295 87002..87979 + 978 WP_032701292.1 IS5 family transposase -
QEP68_RS28300 88430..89486 + 1057 Protein_104 IS630 family transposase -
QEP68_RS28305 89512..89808 - 297 WP_004666829.1 coronamic acid biosynthesis protein CmaL -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 65094..95254 30160
- inside Conjugative plasmid - - 1..181117 181117


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10185.64 Da        Isoelectric Point: 5.0749

>T278653 WP_004662083.1 NZ_CP123216:c85060-84788 [Pseudomonas amygdali pv. aesculi]
VLVEWLPQALEALEEIAGYLAERNPYAAEQMQATLEATVEALPLHPYIHRPGRVPGTREAVVHPNYLVVYRVGTERISIV
DVLHARQEYP

Download         Length: 273 bp

Antitoxin


Download         Length: 62 a.a.        Molecular weight: 7296.25 Da        Isoelectric Point: 8.7721

>AT278653 WP_003381808.1 NZ_CP123216:c85235-85050 [Pseudomonas amygdali pv. aesculi]
MSIQLDPRVSEFETQEQADNYDRWFRLRIERSLADPRPPVPHDEAMARVRAMIEAKRRRAS

Download         Length: 186 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0N8QF55

Antitoxin

Source ID Structure
AlphaFold DB A0A2V0QZQ1

References