Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RelE(toxin) |
Location | 91444..91891 | Replicon | plasmid pCOR1804 |
Accession | NZ_CP123214 | ||
Organism | Pseudomonas amygdali pv. aesculi strain 1804 |
Toxin (Protein)
Gene name | relE | Uniprot ID | E7PTW5 |
Locus tag | QEP69_RS29885 | Protein ID | WP_004662083.1 |
Coordinates | 91619..91891 (+) | Length | 91 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A3M4C5H0 |
Locus tag | QEP69_RS29880 | Protein ID | WP_005730485.1 |
Coordinates | 91444..91629 (+) | Length | 62 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QEP69_RS29850 | 87429..88463 | - | 1035 | WP_243580921.1 | IS110 family transposase | - |
QEP69_RS29855 | 88574..89264 | - | 691 | Protein_88 | Tn3 family transposase | - |
QEP69_RS29860 | 89417..89620 | + | 204 | Protein_89 | Tn3 family transposase | - |
QEP69_RS29865 | 89661..89834 | + | 174 | Protein_90 | helix-turn-helix domain-containing protein | - |
QEP69_RS29870 | 89877..90857 | + | 981 | WP_057403839.1 | IS5-like element ISPsy2 family transposase | - |
QEP69_RS29875 | 91115..91393 | + | 279 | WP_024661522.1 | hypothetical protein | - |
QEP69_RS29880 | 91444..91629 | + | 186 | WP_005730485.1 | hypothetical protein | Antitoxin |
QEP69_RS29885 | 91619..91891 | + | 273 | WP_004662083.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
QEP69_RS29890 | 91995..92708 | + | 714 | WP_044322701.1 | YecA family protein | - |
QEP69_RS29895 | 92782..93525 | + | 744 | WP_004667958.1 | hypothetical protein | - |
QEP69_RS29900 | 93522..94334 | + | 813 | WP_005730366.1 | DUF3037 domain-containing protein | - |
QEP69_RS29905 | 94939..95643 | - | 705 | WP_060409903.1 | GNAT family N-acetyltransferase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..114960 | 114960 | |
- | inside | IScluster/Tn | - | - | 83784..110245 | 26461 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 91 a.a. Molecular weight: 10185.64 Da Isoelectric Point: 5.0749
>T278649 WP_004662083.1 NZ_CP123214:91619-91891 [Pseudomonas amygdali pv. aesculi]
VLVEWLPQALEALEEIAGYLAERNPYAAEQMQATLEATVEALPLHPYIHRPGRVPGTREAVVHPNYLVVYRVGTERISIV
DVLHARQEYP
VLVEWLPQALEALEEIAGYLAERNPYAAEQMQATLEATVEALPLHPYIHRPGRVPGTREAVVHPNYLVVYRVGTERISIV
DVLHARQEYP
Download Length: 273 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0N8QF55 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3M4C5H0 |