278649

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 91444..91891 Replicon plasmid pCOR1804
Accession NZ_CP123214
Organism Pseudomonas amygdali pv. aesculi strain 1804

Toxin (Protein)


Gene name relE Uniprot ID E7PTW5
Locus tag QEP69_RS29885 Protein ID WP_004662083.1
Coordinates 91619..91891 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A3M4C5H0
Locus tag QEP69_RS29880 Protein ID WP_005730485.1
Coordinates 91444..91629 (+) Length 62 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QEP69_RS29850 87429..88463 - 1035 WP_243580921.1 IS110 family transposase -
QEP69_RS29855 88574..89264 - 691 Protein_88 Tn3 family transposase -
QEP69_RS29860 89417..89620 + 204 Protein_89 Tn3 family transposase -
QEP69_RS29865 89661..89834 + 174 Protein_90 helix-turn-helix domain-containing protein -
QEP69_RS29870 89877..90857 + 981 WP_057403839.1 IS5-like element ISPsy2 family transposase -
QEP69_RS29875 91115..91393 + 279 WP_024661522.1 hypothetical protein -
QEP69_RS29880 91444..91629 + 186 WP_005730485.1 hypothetical protein Antitoxin
QEP69_RS29885 91619..91891 + 273 WP_004662083.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QEP69_RS29890 91995..92708 + 714 WP_044322701.1 YecA family protein -
QEP69_RS29895 92782..93525 + 744 WP_004667958.1 hypothetical protein -
QEP69_RS29900 93522..94334 + 813 WP_005730366.1 DUF3037 domain-containing protein -
QEP69_RS29905 94939..95643 - 705 WP_060409903.1 GNAT family N-acetyltransferase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..114960 114960
- inside IScluster/Tn - - 83784..110245 26461


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-89)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 91 a.a.        Molecular weight: 10185.64 Da        Isoelectric Point: 5.0749

>T278649 WP_004662083.1 NZ_CP123214:91619-91891 [Pseudomonas amygdali pv. aesculi]
VLVEWLPQALEALEEIAGYLAERNPYAAEQMQATLEATVEALPLHPYIHRPGRVPGTREAVVHPNYLVVYRVGTERISIV
DVLHARQEYP

Download         Length: 273 bp


Antitoxin


Download         Length: 62 a.a.        Molecular weight: 7292.18 Da        Isoelectric Point: 7.2040

>AT278649 WP_005730485.1 NZ_CP123214:91444-91629 [Pseudomonas amygdali pv. aesculi]
MSIQLDPRVSEFETQEQADNYDRWFRQRIEHSLADPRPPVPHDEAMARVRAMIEAKRRRAS

Download         Length: 186 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0N8QF55


Antitoxin

Source ID Structure
AlphaFold DB A0A3M4C5H0

References