278642

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4180494..4181013 Replicon chromosome
Accession NZ_CP123209
Organism Pseudomonas amygdali pv. aesculi strain 1804

Toxin (Protein)


Gene name relE Uniprot ID Q48Q48
Locus tag QEP69_RS19050 Protein ID WP_002551445.1
Coordinates 4180494..4180784 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S6UWW5
Locus tag QEP69_RS19055 Protein ID WP_002551444.1
Coordinates 4180774..4181013 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QEP69_RS19025 4176164..4176718 - 555 WP_010205022.1 histidine phosphatase family protein -
QEP69_RS19030 4176774..4178033 + 1260 WP_005730411.1 IS256-like element ISPsy17 family transposase -
QEP69_RS19035 4178265..4178606 - 342 WP_005734122.1 DUF5713 family protein -
QEP69_RS19040 4178796..4179218 + 423 WP_005734119.1 DUF1493 family protein -
QEP69_RS19045 4179524..4180261 + 738 WP_005734118.1 hypothetical protein -
QEP69_RS19050 4180494..4180784 - 291 WP_002551445.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QEP69_RS19055 4180774..4181013 - 240 WP_002551444.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
QEP69_RS19060 4181177..4181650 - 474 WP_010214544.1 GNAT family N-acetyltransferase -
QEP69_RS19065 4181752..4182300 - 549 WP_010214542.1 GNAT family N-acetyltransferase -
QEP69_RS19070 4182460..4182954 + 495 WP_004667254.1 hypothetical protein -
QEP69_RS19075 4182988..4184262 - 1275 WP_004667253.1 OprD family porin -
QEP69_RS19080 4184477..4184710 - 234 WP_002551440.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11316.19 Da        Isoelectric Point: 10.2579

>T278642 WP_002551445.1 NZ_CP123209:c4180784-4180494 [Pseudomonas amygdali pv. aesculi]
MTYNLEFDARALKEWHKLGDTVRQQLKKKLATILVAPRVEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVVVFVVAVDK
REREEVYRKATDRLGR

Download         Length: 291 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8955.34 Da        Isoelectric Point: 4.6017

>AT278642 WP_002551444.1 NZ_CP123209:c4181013-4180774 [Pseudomonas amygdali pv. aesculi]
MASINVRIDDDLKARAYLELEKLGVTPSELLRQTLQYVAERGQLPFKTVLMTEEDEALLATVRERLAAPQRVKVSLDDL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2G4DBS4

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8M1G9

References