278641

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 53990..54467 Replicon plasmid pPae6617P
Accession NZ_CP123207
Organism Pseudomonas amygdali pv. aesculi strain 6617

Toxin (Protein)


Gene name pasB Uniprot ID A0A0P9I0A0
Locus tag QEP71_RS29225 Protein ID WP_005730593.1
Coordinates 53990..54256 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID A0A3R8W5Z2
Locus tag QEP71_RS29230 Protein ID WP_005730594.1
Coordinates 54240..54467 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QEP71_RS29200 49239..49517 - 279 Protein_50 type II toxin-antitoxin system YafQ family toxin -
QEP71_RS29205 49504..49767 - 264 WP_005730323.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
QEP71_RS29210 49972..50418 + 447 WP_232289920.1 type III effector -
QEP71_RS29215 50741..51971 + 1231 WP_280124519.1 IS91 family transposase -
QEP71_RS29220 52691..53725 - 1035 WP_280124518.1 IS110-like element ISPsy16 family transposase -
QEP71_RS29225 53990..54256 - 267 WP_005730593.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QEP71_RS29230 54240..54467 - 228 WP_005730594.1 hypothetical protein Antitoxin
QEP71_RS29235 54730..55653 - 924 WP_060406699.1 recombinase family protein -
QEP71_RS29240 55860..56099 + 240 WP_010216588.1 ribbon-helix-helix domain-containing protein -
QEP71_RS29245 56099..56518 + 420 WP_005734741.1 putative toxin-antitoxin system toxin component, PIN family -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..71577 71577
- inside IScluster/Tn - - 3390..61098 57708


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10201.73 Da        Isoelectric Point: 10.2748

>T278641 WP_005730593.1 NZ_CP123207:c54256-53990 [Pseudomonas amygdali pv. aesculi]
MAWTIDYTDTAKTQLRKLDKQSAKRILDFMDERVSSRDDPRTTGKALTGPLGGLWRYRVGDFRVICEIQDGALRILVVQL
GNRREVYR

Download         Length: 267 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8540.57 Da        Isoelectric Point: 4.6135

>AT278641 WP_005730594.1 NZ_CP123207:c54467-54240 [Pseudomonas amygdali pv. aesculi]
MATSIRLAPETEQRLDFLATSTGRTKAYYLREIIDHGLTDLEDYYLAAEVLERVRKNTEVVHSAADVRKDLGLDD

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0P9I0A0

Antitoxin

Source ID Structure
AlphaFold DB A0A3R8W5Z2

References