Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/ParE-RelB |
Location | 4976536..4977055 | Replicon | chromosome |
Accession | NZ_CP123204 | ||
Organism | Pseudomonas amygdali pv. aesculi strain 6617 |
Toxin (Protein)
Gene name | relE | Uniprot ID | Q48Q48 |
Locus tag | QEP71_RS22770 | Protein ID | WP_002551445.1 |
Coordinates | 4976536..4976826 (-) | Length | 97 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | S6UWW5 |
Locus tag | QEP71_RS22775 | Protein ID | WP_002551444.1 |
Coordinates | 4976816..4977055 (-) | Length | 80 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QEP71_RS22745 | 4972206..4972760 | - | 555 | WP_010205022.1 | histidine phosphatase family protein | - |
QEP71_RS22750 | 4972816..4974075 | + | 1260 | WP_005730411.1 | IS256-like element ISPsy17 family transposase | - |
QEP71_RS22755 | 4974307..4974648 | - | 342 | WP_005734122.1 | DUF5713 family protein | - |
QEP71_RS22760 | 4974838..4975260 | + | 423 | WP_005734119.1 | DUF1493 family protein | - |
QEP71_RS22765 | 4975566..4976303 | + | 738 | WP_005734118.1 | hypothetical protein | - |
QEP71_RS22770 | 4976536..4976826 | - | 291 | WP_002551445.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
QEP71_RS22775 | 4976816..4977055 | - | 240 | WP_002551444.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
QEP71_RS22780 | 4977219..4977692 | - | 474 | WP_010214544.1 | GNAT family N-acetyltransferase | - |
QEP71_RS22785 | 4977794..4978342 | - | 549 | WP_010214542.1 | GNAT family N-acetyltransferase | - |
QEP71_RS22790 | 4978502..4978996 | + | 495 | WP_004667254.1 | hypothetical protein | - |
QEP71_RS22795 | 4979030..4980304 | - | 1275 | WP_004667253.1 | OprD family porin | - |
QEP71_RS22800 | 4980519..4980752 | - | 234 | WP_002551440.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 4911324..4987737 | 76413 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 11316.19 Da Isoelectric Point: 10.2579
>T278635 WP_002551445.1 NZ_CP123204:c4976826-4976536 [Pseudomonas amygdali pv. aesculi]
MTYNLEFDARALKEWHKLGDTVRQQLKKKLATILVAPRVEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVVVFVVAVDK
REREEVYRKATDRLGR
MTYNLEFDARALKEWHKLGDTVRQQLKKKLATILVAPRVEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVVVFVVAVDK
REREEVYRKATDRLGR
Download Length: 291 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2G4DBS4 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0K8M1G9 |